Recurrent Clostridium difficile Infection in Children: Patient Risk Factors and Markers of Intestinal Inflammation

• Published in: The Pediatric infectious disease journal Vol. 36; no. 4; p. 379
• Main Authors: Nicholson, Maribeth R, Crews, Jonathan D, Starke, Jeffrey R, Jiang, Zhi-Dong, DuPont, Herbert, Edwards, Kathryn
• Format: Journal Article
• Language: English
• Published: United States 01.04.2017
• Subjects: Adolescent; Biomarkers - analysis; Child; Child, Preschool; Clostridium difficile; Clostridium Infections - epidemiology; Cytokines - analysis; Feces - chemistry; Female; Humans; Infant; Inflammation - metabolism; Intestines - physiopathology; Male; Prospective Studies; Recurrence; Risk Factors

The management of Clostridium difficile infection (CDI) in children is complicated by recurrence rates of 20%-30%. The identification of risk factors associated with recurrent disease might allow early recognition of those children at highest risk. Pediatric patients with CDI were identified through...