Drug sensitivity and isoenzyme type in cloned lines of Plasmodium falciparum

• Published in: The American journal of tropical medicine and hygiene Vol. 33; no. 2; pp. 212 - 219
• Main Authors: Graves, P.M, Carter, R, Keystone, J.S, Seeley, D.C., jr
• Format: Journal Article
• Language: English
• Published: United States 01.03.1984
• Subjects: Africa; Animals; Brazil; Chloroquine - pharmacology; Clone Cells - drug effects; Clone Cells - enzymology; clones; Dose-Response Relationship, Drug; drug resistance; Drug Resistance, Microbial; enzymes; genetics; Glucose-6-Phosphate Isomerase - classification; Isoenzymes - classification; Plasmodium falciparum; Plasmodium falciparum - drug effects; Plasmodium falciparum - enzymology; Protozoa; Pyrimethamine - pharmacology; Treatment and control; variation; Brazil; Africa

Plasmodium falciparum clones (derived by limiting dilution from recent isolates from Africa and Brazil) characterized for pyrimethamine and chloroquine sensitivity and/or isoenzyme type, different levels of drug sensitivity among clones