Cardiovascular toxicity of decabrominated diphenyl ethers (BDE-209) and decabromodiphenyl ethane (DBDPE) in rats

• Published in: Chemosphere (Oxford) Vol. 223; pp. 675 - 685
• Main Authors: Jing, Li, Sun, Yanmin, Wang, Yuwei, Liang, Baolu, Chen, Tian, Zheng, Dan, Zhao, Xuezhen, Zhou, Xianqing, Sun, Zhiwei, Shi, Zhixiong
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.05.2019
• Subjects: animal models; antioxidants; aorta; blood serum; Brominated flame retardants; Cardiovascular toxicity; corn oil; creatine kinase; Decabrominated diphenyl ether; Decabromodiphenyl ethane; diphenyl ethers; endothelins; enzyme activity; ethane; heart; inflammation; intercellular adhesion molecule-1; interleukin-10; interleukin-1beta; interleukin-6; laboratory animals; lactate dehydrogenase; males; oral administration; oral exposure; oxidative stress; Rat; rats; toxicity; tumor necrosis factor-alpha; Decabrominated diphenyl ether; Decabromodiphenyl ethane; Rat; Cardiovascular toxicity; Brominated flame retardants

Recent reports indicated that decabrominated diphenyl ether (BDE-209) and decabromodiphenyl ethane (DBDPE) exist extensively in the environment. The toxicity of BDE-209 has been reported in quite a few studies, whereas the data of DBDPE are relatively rare. However, databases regarding cardiovascula...