Development of a Monte Carlo-based scatter correction method for total-body PET using the uEXPLORER PET/CT scanner

• Published in: Physics in medicine & biology Vol. 69; no. 4; pp. 45033 - 45044
• Main Authors: Bayerlein, Reimund, Spencer, Benjamin A, Leung, Edwin K, Omidvari, Negar, Abdelhafez, Yasser G, Wang, Qian, Nardo, Lorenzo, Cherry, Simon R, Badawi, Ramsey D
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 21.02.2024
• Subjects: Algorithms; Humans; Image Processing, Computer-Assisted - methods; Monte Carlo (MC) simulation; Monte Carlo Method; Phantoms, Imaging; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography - methods; Reproducibility of Results; scatter correction (SC); Scattering, Radiation; total-body PET; Monte Carlo (MC) simulation; scatter correction (SC); total-body PET

Objective. This study presents and evaluates a robust Monte Carlo-based scatter correction (SC) method for long axial field of view (FOV) and total-body positron emission tomography (PET) using the uEXPLORER total-body PET/CT scanner. Approach. Our algorithm utilizes the Monte Carlo (MC) tool SimSET...