Histopathological, Immunohistochemical and In-Situ Hybridization Findings in Suckling Rats Experimentally Infected With Akabane Genogroups Ⅰ and Ⅱ, Aino and Peaton Viruses

• Published in: Journal of comparative pathology Vol. 187; pp. 27 - 39
• Main Authors: Kimura, Kumiko, Yanase, Tohru, Kato, Tomoko
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.08.2021
• Subjects: Akabane orthobunyavirus; animal models; arbovirus; arboviruses; brain; cattle; cross reaction; encephalitis; heart; histopathology; immunohistochemistry; in situ hybridization; inflammation; necrosis; pathogenesis; polyclonal antibodies; rabbits; rat model; RNA; sheep; skeletal muscle; viral antigens; rat model; immunohistochemistry; in-situ hybridization; arbovirus

Akabane, Aino and Peaton viruses are closely related arthropod-borne viruses in the genus Orthobunyavirus of the family Peribunyaviridae that can cause congenital abnormalities in cattle, sheep and goats. East Asian Akabane virus strains are subdivided into genogroups Ⅰ and Ⅱ, and the former can als...