A Family of Spore Lipoproteins Stabilizes the Germination Apparatus by Altering Inner Spore Membrane Fluidity in Bacillus subtilis Spores

• Published in: Journal of bacteriology Vol. 205; no. 10; p. e0014223
• Main Authors: Flores, Matthew J., Duricy, Kate, Choudhary, Shreya, Laue, Michael, Popham, David L.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 26.10.2023
• Subjects: Bacillus subtilis - metabolism; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Bacteriology; Cations; Dormancy; Electron microscopy; Fluidity; Genomes; Germination; Humans; Lipoproteins; Lipoproteins - genetics; Lipoproteins - metabolism; Macromolecules; Membrane Fluidity; Membrane Proteins - genetics; Membrane Proteins - metabolism; Membranes; Molecular structure; Nutrient release; Persistent Vegetative State - metabolism; Protein interaction; Proteins; Rehydration; Spore germination; Spores; Spores, Bacterial - metabolism; Strains (organisms); endospore; membrane; lipoprotein; spores

Bacterial spores exhibit extreme longevity and resistance to many killing agents, and are thus problematic agents of several diseases and of food spoilage. However, to cause disease or spoilage, germination of the spore and return to the vegetative state is necessary. Dormant bacterial spores underg...