Circulating cell-free DNA as a biomarker for molecular diagnosis of Neurocysticercosis

• Published in: Journal of the neurological sciences Vol. 461; p. 123039
• Main Authors: Mehta, Yashvi, Kaur, Upninder, Shree, Ritu, Modi, Manish, Lal, Vivek, Sehgal, Rakesh
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.06.2024
• Subjects: Adolescent; Adult; Biomarkers - blood; Cell-free DNA; Cell-Free Nucleic Acids - blood; Diagnosis; Female; Humans; LAMP; Male; Middle Aged; Molecular diagnosis; Molecular Diagnostic Techniques - methods; Neurocysticercosis; Neurocysticercosis - blood; Neurocysticercosis - diagnosis; Neurocysticercosis - genetics; Neurology; Taenia solium - genetics; Taenia solium - isolation & purification; Young Adult; Cell-free DNA; Neurocysticercosis; Molecular diagnosis; LAMP; Diagnosis

Taenia solium is a widespread zoonotic tapeworm that predominantly affects regions of Latin America, South and South-East Asia, and Sub-Saharan Africa. Neurocysticercosis (NCC), the presence of T. solium cysts in the brain is associated with diverse clinical manifestations, such as epilepsy, seizure...