The distribution of persistent, mobile and toxic (PMT) pharmaceuticals and personal care products monitored across Chinese water resources

[Display omitted] •First PMT assessment for over 400 pharmaceuticals and personal care products (PPCPs).•Compilation of PPCPs in Chinese surface water, drinking water & groundwater.•Over a third of PPCPs detected in water suspected to meet the PMT criteria.•Efforts to reduce emissions of PMT-PPC...

Full description

Saved in:
Bibliographic Details
Published inJournal of hazardous materials letters Vol. 2; p. 100026
Main Authors Huang, Chen, Jin, Biao, Han, Min, Yu, Yang, Zhang, Gan, Arp, Hans Peter H.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.11.2021
Elsevier
Subjects
Online AccessGet full text

Cover

Loading…
Abstract [Display omitted] •First PMT assessment for over 400 pharmaceuticals and personal care products (PPCPs).•Compilation of PPCPs in Chinese surface water, drinking water & groundwater.•Over a third of PPCPs detected in water suspected to meet the PMT criteria.•Efforts to reduce emissions of PMT-PPCPs in China are encouraged. Hazard classifications have recently been introduced for persistent, mobile and toxic (PMT) and very persistent and very mobile (vPvM) substances, which are those that negatively impact water resources if substantially emitted into the environment. Many pharmaceuticals and personal care products (PPCPs) may meet this classification. Our study focused on 169 detected PPCPs in surface water, groundwater and drinking water in China among a total of 432 PPCPs that were monitored for across 75 studies. We assessed if these could be classified as PMT/vPvM substances based on the recent European criteria for industrial substances. For most PPCPs, persistency half-life data were lacking; therefore, definitive classifications could not be made. In surface water, 52 (37.7 %) of the detected PPCPs met, or were strongly suspected to meet, the PMT/vPvM criteria. Over half of these were antibiotic compounds. The industrialized Yangtze, Haihe and Pearl river basins were the most impacted. We hypothesized the proportion of PPCPs monitored meeting the PMT/vPvM criteria in drinking water and groundwater would be larger than surface water. This was supported as 44.3 % of PPCPs in these media met, or based on weight-of-evidence likely meet, the PMT/vPvM criteria; though, a definitive comparison was hindered by a lack of persistence data.
AbstractList Hazard classifications have recently been introduced for persistent, mobile and toxic (PMT) and very persistent and very mobile (vPvM) substances, which are those that negatively impact water resources if substantially emitted into the environment. Many pharmaceuticals and personal care products (PPCPs) may meet this classification. Our study focused on 169 detected PPCPs in surface water, groundwater and drinking water in China among a total of 432 PPCPs that were monitored for across 75 studies. We assessed if these could be classified as PMT/vPvM substances based on the recent European criteria for industrial substances. For most PPCPs, persistency half-life data were lacking; therefore, definitive classifications could not be made. In surface water, 52 (37.7 %) of the detected PPCPs met, or were strongly suspected to meet, the PMT/vPvM criteria. Over half of these were antibiotic compounds. The industrialized Yangtze, Haihe and Pearl river basins were the most impacted. We hypothesized the proportion of PPCPs monitored meeting the PMT/vPvM criteria in drinking water and groundwater would be larger than surface water. This was supported as 44.3 % of PPCPs in these media met, or based on weight-of-evidence likely meet, the PMT/vPvM criteria; though, a definitive comparison was hindered by a lack of persistence data.
[Display omitted] •First PMT assessment for over 400 pharmaceuticals and personal care products (PPCPs).•Compilation of PPCPs in Chinese surface water, drinking water & groundwater.•Over a third of PPCPs detected in water suspected to meet the PMT criteria.•Efforts to reduce emissions of PMT-PPCPs in China are encouraged. Hazard classifications have recently been introduced for persistent, mobile and toxic (PMT) and very persistent and very mobile (vPvM) substances, which are those that negatively impact water resources if substantially emitted into the environment. Many pharmaceuticals and personal care products (PPCPs) may meet this classification. Our study focused on 169 detected PPCPs in surface water, groundwater and drinking water in China among a total of 432 PPCPs that were monitored for across 75 studies. We assessed if these could be classified as PMT/vPvM substances based on the recent European criteria for industrial substances. For most PPCPs, persistency half-life data were lacking; therefore, definitive classifications could not be made. In surface water, 52 (37.7 %) of the detected PPCPs met, or were strongly suspected to meet, the PMT/vPvM criteria. Over half of these were antibiotic compounds. The industrialized Yangtze, Haihe and Pearl river basins were the most impacted. We hypothesized the proportion of PPCPs monitored meeting the PMT/vPvM criteria in drinking water and groundwater would be larger than surface water. This was supported as 44.3 % of PPCPs in these media met, or based on weight-of-evidence likely meet, the PMT/vPvM criteria; though, a definitive comparison was hindered by a lack of persistence data.
ArticleNumber 100026
Author Jin, Biao
Han, Min
Zhang, Gan
Yu, Yang
Huang, Chen
Arp, Hans Peter H.
Author_xml – sequence: 1
  givenname: Chen
  surname: Huang
  fullname: Huang, Chen
  organization: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China
– sequence: 2
  givenname: Biao
  surname: Jin
  fullname: Jin, Biao
  email: jinbiao@gig.ac.cn
  organization: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China
– sequence: 3
  givenname: Min
  surname: Han
  fullname: Han, Min
  organization: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China
– sequence: 4
  givenname: Yang
  surname: Yu
  fullname: Yu, Yang
  organization: Solid Waste and Chemicals Management Center, Ministry of Ecology and Environment (MEE), Beijing, 100029, China
– sequence: 5
  givenname: Gan
  surname: Zhang
  fullname: Zhang, Gan
  organization: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, 510640, China
– sequence: 6
  givenname: Hans Peter H.
  surname: Arp
  fullname: Arp, Hans Peter H.
  organization: Norwegian Geotechnical Institute (NGI), P.O. Box 3930, Ullevaal Stadion, N-0806, Oslo, Norway
BookMark eNp9kc2OEzEQhEdokViWfQFOPoJEgu0ZezISFxTxs9IiOISz5Wm3iaOJHbUd_h5hn3o9CUiIw57cKvsrubqeNhcxRWya54IvBRf69W65tb-npeRSVIFzqR81l1JrvRiE4Bf_zE-a65x385OVEG3LL5u7zRaZC7lQGI8lpMiSZwekXCWM5RXbpzFMyGx0rKSfAdiLL582L9lha2lvASsDdsqn-xlL0U4MLCE7UHJHKLk6xFASoWMWKOXM1tsQMSP7YQsSI8zpSID5WfPYVyu8_nNeNV_fv9usPy5uP3-4Wb-9XUAneFmAlLrv3ODavmv7sXW61RpXyJWUdnDK93Xoe68G67hQuuZ20KIC9N3gBbZXzc3Z1yW7MwcKe0u_TLLBnIRE34ylGmtCY6VznfAIqIduGNVKgxJKguJ-7BX01Wt19jolI_QGQrHzHgvZMBnBzVyR2Zm5IjNXZM4VVVT-h_79yoPQmzOEdUHfA5LJEDACukAIpSYID-H3RkSuhQ
CitedBy_id crossref_primary_10_1007_s00506_022_00870_9
crossref_primary_10_3390_jmse12071133
crossref_primary_10_3390_resources11110105
crossref_primary_10_1021_acs_est_4c01201
crossref_primary_10_1021_acsestwater_4c00977
crossref_primary_10_1021_acsenvironau_2c00024
crossref_primary_10_1016_j_jenvman_2022_115703
crossref_primary_10_1039_D2EM00034B
crossref_primary_10_26634_jms_11_1_20158
crossref_primary_10_1186_s12302_024_00932_7
crossref_primary_10_1021_acs_est_2c06155
crossref_primary_10_2166_ws_2024_261
crossref_primary_10_20517_wecn_2023_18
crossref_primary_10_3390_w16131888
crossref_primary_10_1039_D4CP02969K
crossref_primary_10_1016_j_isci_2024_109012
crossref_primary_10_1021_acs_est_1c02131
crossref_primary_10_1039_D3EW00160A
crossref_primary_10_2139_ssrn_4128775
crossref_primary_10_1021_acsestwater_4c00731
crossref_primary_10_1021_acs_estlett_3c00943
crossref_primary_10_3390_microorganisms10061101
crossref_primary_10_1016_j_scitotenv_2023_167355
crossref_primary_10_1016_j_comtox_2022_100254
crossref_primary_10_3390_toxics13010006
crossref_primary_10_1021_acs_est_2c07774
Cites_doi 10.1016/j.jhazmat.2013.08.040
10.1016/j.scitotenv.2020.137652
10.1186/s12302-020-00440-4
10.1016/j.envint.2019.105454
10.1021/acs.est.0c01898
10.1016/j.chemosphere.2016.02.109
10.1016/j.envpol.2017.10.032
10.1021/acs.est.6b03338
10.1021/acs.est.0c04281
10.1021/acs.est.9b06379
10.1021/acs.est.5b00729
10.1007/s11356-019-06047-4
10.1016/j.ecoenv.2016.10.006
10.1016/j.scitotenv.2017.08.009
10.1016/j.envint.2019.105306
10.1007/s12665-016-6008-4
10.1007/s13157-014-0561-y
10.1016/j.watres.2020.116017
10.1016/j.watres.2020.115699
10.1016/j.scitotenv.2017.02.200
10.1016/j.envres.2020.109386
10.1016/j.scitotenv.2014.05.068
10.1016/j.watres.2014.08.053
10.1016/j.watres.2017.12.029
10.1021/es3002713
10.1016/j.jenvman.2019.109732
10.1039/C7EM00158D
10.2166/wh.2019.250
10.1021/acs.est.0c05257
10.1007/s11356-017-8999-0
10.1016/j.scitotenv.2019.133991
10.1016/j.scitotenv.2017.03.281
10.1039/C6EM00062B
10.1038/srep34928
ContentType Journal Article
Copyright 2021 The Author(s)
Copyright_xml – notice: 2021 The Author(s)
DBID 6I.
AAFTH
AAYXX
CITATION
DOA
DOI 10.1016/j.hazl.2021.100026
DatabaseName ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
CrossRef
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
DatabaseTitleList

Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
DeliveryMethod fulltext_linktorsrc
EISSN 2666-9110
ExternalDocumentID oai_doaj_org_article_a2dd41fece6949b586c5152c50fb75c7
10_1016_j_hazl_2021_100026
S2666911021000149
GroupedDBID 6I.
AAEDW
AAFTH
AAXUO
AFPKN
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
EBS
FDB
GROUPED_DOAJ
M~E
OK1
AAFWJ
AALRI
AAYWO
AAYXX
ACVFH
ADCNI
ADVLN
AEUPX
AFJKZ
AFPUW
AIGII
AITUG
AKBMS
AKYEP
APXCP
CITATION
ID FETCH-LOGICAL-c410t-c22674d9d37437b3d6366e8e0522a9d5f752277f59ad0156911dc3e5cef49f1e3
IEDL.DBID DOA
ISSN 2666-9110
IngestDate Wed Aug 27 01:32:30 EDT 2025
Tue Jul 01 01:31:44 EDT 2025
Thu Apr 24 22:58:38 EDT 2025
Fri Feb 23 02:42:02 EST 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Keywords PPCP
Drinking water
Groundwater
Surface water
vPvM
Language English
License This is an open access article under the CC BY-NC-ND license.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c410t-c22674d9d37437b3d6366e8e0522a9d5f752277f59ad0156911dc3e5cef49f1e3
OpenAccessLink https://doaj.org/article/a2dd41fece6949b586c5152c50fb75c7
ParticipantIDs doaj_primary_oai_doaj_org_article_a2dd41fece6949b586c5152c50fb75c7
crossref_citationtrail_10_1016_j_hazl_2021_100026
crossref_primary_10_1016_j_hazl_2021_100026
elsevier_sciencedirect_doi_10_1016_j_hazl_2021_100026
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate November 2021
2021-11-00
2021-11-01
PublicationDateYYYYMMDD 2021-11-01
PublicationDate_xml – month: 11
  year: 2021
  text: November 2021
PublicationDecade 2020
PublicationTitle Journal of hazardous materials letters
PublicationYear 2021
Publisher Elsevier B.V
Elsevier
Publisher_xml – name: Elsevier B.V
– name: Elsevier
References Peng, Pan, Zhang, Zhang, Windfeld, Salvito, Selck, Van den Brink, Ying (bib0150) 2017; 589
Hale, Arp, Schliebner, Neumann (bib0085) 2020; 32
(retrieved on March, 2021).
OECD; QSAR Toolbox, Version 4.4.1; Organisation for Economic Co-operation and Development.
Wang, Liu, Lu, Liu, Meng, Zhang, Zhang, Wang, Guo (bib0190) 2019; 26
Tran, Reinhard, Gin (bib0175) 2018; 133
Su, Cui, Liu, Zhang, Baninla (bib0170) 2020; 720
Ben, Hu, Zhang, Wu, Wong, Wang, Andrews, Zheng (bib0020) 2020; 175
Yang, He, Su, Cui, Huang, Wang (bib0200) 2017; 24
Zhou, Ying, Wang, Liu (bib0230) 2016; 6
Dong, Zhang, Liu, Guo, Hua (bib0045) 2016; 75
Yao, Yan, Lian, Yang, Wan, Dong, Song (bib0215) 2018; 236
EU (bib0060) 2020
Hale, Arp, Schliebner, Neumann (bib0080) 2020
Bu, Wang, Huang, Deng, Yu (bib0025) 2013; 262
Wang, Du, Yang, Liu, Zhang, Li, Zhang, Wang (bib0185) 2017; 609
NIH. PubChem; National Institute of Health.
Wang, Walker, Muir, Nagatani-Yoshida (bib0195) 2020; 54
Lin, Yu, Chen (bib0110) 2016; 152
Zhang, Ying, Pan, Liu, Zhao (bib0220) 2015; 49
Zhang, Sun, Jiang, Zeng, Sunderland, Muir (bib0225) 2020; 54
Reemtsma, Berger, Arp, Gallard, Knepper, Neumann, Quintana, Voogt (bib0160) 2016; 50
European Chemicals Agency (bib0065) 2017
Arp, Brown, Berger, Hale (bib0015) 2017; 19
ECHA. C&L Inventory.
Lv, Zhang, Chen, Ye, Han, Jin (bib0120) 2019; 17
De Baat, Van der Oost, Van der Lee, Wieringa, Hamers, Verdonschot, De Voogt, Kraak (bib0040) 2020; 183
Peng, Ou, Wang, Wang, Huang, Jin, Tan (bib0145) 2014; 490
ChemAxon; ChemAxon
Yao, Wang, Tong, Deng, Li, Gan, Guo, Dong, Duan, Zhao (bib0210) 2017; 135
Neumann, Schliebner (bib0130) 2019
US EPA. CompTox Chemistry Dashboard. The United States Environmental Protection Agency.
Jin, Huang, Yu, Zhang, Arp (bib0095) 2020
Strempel, Scheringer, Ng, Hungerbühler (bib0165) 2012; 46
Arnot, Gouin, Mackay (bib0005) 2005
Cheng, Xie, Yu, Liu, Zhao, Cui, Bai (bib0035) 2016; 36
(http://chemaxon.com, retrieved on November, 2020).
HESI (bib0090) 2020
Liu, Jin, Feng, Wang, Wu, Johnson, Xiao, Hollert, Giesy (bib0115) 2020; 136
Yang, Zhou, Shi, Meng, He, Yang, Yoon, Kim, Kwon, Khim, Wang (bib0205) 2020; 135
Petrie, Barden, Kasprzyk-Hordern (bib0155) 2015; 72
(retrieved September, 2020).
Arp, Hale (bib0010) 2019
Goldenman, Fernandes, Holland, Tugran, Nordin, Schoumacher, McNeill (bib0075) 2019
(retrieved on May to August, 2020).
Feng, Cheng, Zhang, Li, Yu, Feng, Zhang, Xu (bib0070) 2020; 185
MEE, MWR (bib0125) 2018
Li, Ding, Zhang, Liu, Wang (bib0100) 2019; 696
Du, Zhao, Liu, Xie, Wang, Chen (bib0050) 2017; 595
Zhou, Wu, Zhang, Zhao, Zhao (bib0235) 2016; 18
Li, Zhang, Ding, Liu (bib0105) 2020; 253
Liu (10.1016/j.hazl.2021.100026_bib0115) 2020; 136
Arp (10.1016/j.hazl.2021.100026_bib0010) 2019
Tran (10.1016/j.hazl.2021.100026_bib0175) 2018; 133
EU (10.1016/j.hazl.2021.100026_bib0060) 2020
Zhou (10.1016/j.hazl.2021.100026_bib0230) 2016; 6
European Chemicals Agency (10.1016/j.hazl.2021.100026_bib0065) 2017
Yao (10.1016/j.hazl.2021.100026_bib0215) 2018; 236
Arnot (10.1016/j.hazl.2021.100026_bib0005) 2005
Hale (10.1016/j.hazl.2021.100026_bib0080) 2020
Peng (10.1016/j.hazl.2021.100026_bib0145) 2014; 490
Wang (10.1016/j.hazl.2021.100026_bib0195) 2020; 54
Yang (10.1016/j.hazl.2021.100026_bib0200) 2017; 24
Goldenman (10.1016/j.hazl.2021.100026_bib0075) 2019
Li (10.1016/j.hazl.2021.100026_bib0105) 2020; 253
Bu (10.1016/j.hazl.2021.100026_bib0025) 2013; 262
Petrie (10.1016/j.hazl.2021.100026_bib0155) 2015; 72
10.1016/j.hazl.2021.100026_bib0180
Lin (10.1016/j.hazl.2021.100026_bib0110) 2016; 152
MEE (10.1016/j.hazl.2021.100026_bib0125) 2018
Peng (10.1016/j.hazl.2021.100026_bib0150) 2017; 589
10.1016/j.hazl.2021.100026_bib0140
Yang (10.1016/j.hazl.2021.100026_bib0205) 2020; 135
Du (10.1016/j.hazl.2021.100026_bib0050) 2017; 595
Ben (10.1016/j.hazl.2021.100026_bib0020) 2020; 175
Zhou (10.1016/j.hazl.2021.100026_bib0235) 2016; 18
HESI (10.1016/j.hazl.2021.100026_bib0090) 2020
Strempel (10.1016/j.hazl.2021.100026_bib0165) 2012; 46
Lv (10.1016/j.hazl.2021.100026_bib0120) 2019; 17
10.1016/j.hazl.2021.100026_bib0135
De Baat (10.1016/j.hazl.2021.100026_bib0040) 2020; 183
Jin (10.1016/j.hazl.2021.100026_bib0095) 2020
Reemtsma (10.1016/j.hazl.2021.100026_bib0160) 2016; 50
Feng (10.1016/j.hazl.2021.100026_bib0070) 2020; 185
Zhang (10.1016/j.hazl.2021.100026_bib0225) 2020; 54
Li (10.1016/j.hazl.2021.100026_bib0100) 2019; 696
Zhang (10.1016/j.hazl.2021.100026_bib0220) 2015; 49
Cheng (10.1016/j.hazl.2021.100026_bib0035) 2016; 36
Arp (10.1016/j.hazl.2021.100026_bib0015) 2017; 19
Hale (10.1016/j.hazl.2021.100026_bib0085) 2020; 32
Dong (10.1016/j.hazl.2021.100026_bib0045) 2016; 75
Wang (10.1016/j.hazl.2021.100026_bib0190) 2019; 26
10.1016/j.hazl.2021.100026_bib0030
Yao (10.1016/j.hazl.2021.100026_bib0210) 2017; 135
10.1016/j.hazl.2021.100026_bib0055
Neumann (10.1016/j.hazl.2021.100026_bib0130) 2019
Wang (10.1016/j.hazl.2021.100026_bib0185) 2017; 609
Su (10.1016/j.hazl.2021.100026_bib0170) 2020; 720
References_xml – reference: NIH. PubChem; National Institute of Health.
– volume: 609
  start-page: 1423
  year: 2017
  end-page: 1432
  ident: bib0185
  article-title: Occurrence and ecological hazard assessment of selected antibiotics in the surface waters in and around Lake Honghu, China
  publication-title: Sci. Total Environ.
– volume: 183
  year: 2020
  ident: bib0040
  article-title: Advancements in effect-based surface water quality assessment
  publication-title: Water Res.
– volume: 46
  start-page: 5680
  year: 2012
  end-page: 5687
  ident: bib0165
  article-title: Screening for PBT chemicals among the “Existing” and “New” chemicals of the EU
  publication-title: Environ. Sci. Technol.
– year: 2017
  ident: bib0065
  article-title: Guidance on Information Requirements and Chemical Safety Assessment Chapter R.11: PBT/VPvB Assessment Version 3.0; ED-01-17-294-EN-N
– volume: 136
  year: 2020
  ident: bib0115
  article-title: Ecological risk assessment of fifty pharmaceuticals and personal care products (PPCPs) in Chinese surface waters: a proposed multiple-level system
  publication-title: Environ. Int.
– year: 2019
  ident: bib0130
  article-title: Protecting the Sources of Our Drinking Water: the Criteria for Identifying Persistent, Mobile and Toxic (PMT) Substances and Very Persistent and Very Mobile (VPvM) Substances Under EU Regulation REACH (EC) No 1907/2006; Texte 127/2019
– volume: 72
  start-page: 3
  year: 2015
  end-page: 27
  ident: bib0155
  article-title: A review on emerging contaminants in wastewaters and the environment: current knowledge, understudied areas and recommendations for future monitoring
  publication-title: Water Res.
– volume: 133
  start-page: 182
  year: 2018
  end-page: 207
  ident: bib0175
  article-title: Occurrence and fate of emerging contaminants in municipal wastewater treatment plants from different geographical regions-a review
  publication-title: Water Res.
– reference: . (retrieved on March, 2021).
– reference: (retrieved September, 2020).
– volume: 696
  year: 2019
  ident: bib0100
  article-title: Occurrence and ranking of pharmaceuticals in the major rivers of China
  publication-title: Sci. Total Environ.
– reference: OECD; QSAR Toolbox, Version 4.4.1; Organisation for Economic Co-operation and Development.
– volume: 152
  start-page: 1
  year: 2016
  end-page: 9
  ident: bib0110
  article-title: Occurrence, removal and risk assessment of pharmaceutical and personal care products (PPCPs) in an advanced drinking water treatment plant (ADWTP) around Taihu Lake in China
  publication-title: Chemosphere
– reference: US EPA. CompTox Chemistry Dashboard. The United States Environmental Protection Agency.
– volume: 54
  start-page: 2575
  year: 2020
  end-page: 2584
  ident: bib0195
  article-title: Toward a global understanding of chemical pollution: a first comprehensive analysis of national and regional chemical inventories
  publication-title: Environ. Sci. Technol.
– volume: 720
  year: 2020
  ident: bib0170
  article-title: Endocrine disrupting compounds, pharmaceuticals and personal care products in the aquatic environment of China: which chemicals are the prioritized ones?
  publication-title: Sci. Total Environ.
– reference: (retrieved on May to August, 2020).
– volume: 24
  start-page: 15838
  year: 2017
  end-page: 15851
  ident: bib0200
  article-title: Occurrence, distribution, and attenuation of pharmaceuticals and personal care products in the riverside groundwater of the Beiyun River of Beijing, China
  publication-title: Environ. Sci. Pollut. Res.
– year: 2020
  ident: bib0080
  article-title: What’s in a name: Persistent, Mobile, and Toxic (PMT) and Very Persistent and Very Mobile (vPvM) substances
  publication-title: Environ. Sci. Technol.
– volume: 17
  start-page: 477
  year: 2019
  end-page: 489
  ident: bib0120
  article-title: Occurrence and distribution of pharmaceuticals in raw, finished, and drinking water from seven large river basins in China
  publication-title: J. Water Health
– volume: 50
  start-page: 10308
  year: 2016
  end-page: 10315
  ident: bib0160
  article-title: Mind the gap: persistent and mobile organic compounds—water contaminants that slip through
  publication-title: Environ. Sci. Technol.
– year: 2019
  ident: bib0075
  article-title: The Cost of Inaction
– volume: 49
  start-page: 6772
  year: 2015
  end-page: 6782
  ident: bib0220
  article-title: Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling, and linkage to bacterial resistance
  publication-title: Environ. Sci. Technol.
– volume: 595
  start-page: 521
  year: 2017
  end-page: 527
  ident: bib0050
  article-title: Antibiotics in the coastal water of the South Yellow Sea in China: occurrence, distribution and ecological risks
  publication-title: Sci. Total Environ.
– reference: . (http://chemaxon.com, retrieved on November, 2020).
– reference: . (retrieved on May to August, 2020).
– volume: 18
  start-page: 500
  year: 2016
  end-page: 513
  ident: bib0235
  article-title: Occurrence, spatiotemporal distribution, mass balance and ecological risks of antibiotics in subtropical shallow Lake Taihu, China
  publication-title: Environ. Sci. Process. Impacts
– volume: 36
  start-page: 167
  year: 2016
  end-page: 179
  ident: bib0035
  article-title: Occurrence and partitioning of antibiotics in the water column and bottom sediments from the intertidal zone in the Bohai Bay, China
  publication-title: Wetlands
– year: 2020
  ident: bib0060
  article-title: Chemicals Strategy for Sustainability Towards a Toxic-free Environment; COM(2020) 667 Final
– volume: 19
  start-page: 939
  year: 2017
  end-page: 955
  ident: bib0015
  article-title: Ranking REACH registered neutral, ionizable and ionic organic chemicals based on their aquatic persistency and mobility
  publication-title: Environ. Sci. Process. Impacts
– reference: ECHA. C&L Inventory.
– volume: 75
  start-page: 1202
  year: 2016
  ident: bib0045
  article-title: Antibiotics in water and sediments from Liao River in Jilin Province, China: occurrence, distribution, and risk assessment
  publication-title: Environ. Earth Sci.
– year: 2005
  ident: bib0005
  article-title: Practical Methods for Estimating Environmental Biodegradation Rates (No. CEMN Report No. 200503)
– volume: 253
  year: 2020
  ident: bib0105
  article-title: Prioritization of pharmaceuticals in water environment in China based on environmental criteria and risk analysis of top-priority pharmaceuticals
  publication-title: J. Environ. Manage.
– volume: 135
  year: 2020
  ident: bib0205
  article-title: Anthropogenic impacts on the contamination of pharmaceuticals and personal care products (PPCPs) in the coastal environments of the Yellow and Bohai seas
  publication-title: Environ. Int.
– volume: 262
  start-page: 189
  year: 2013
  end-page: 211
  ident: bib0025
  article-title: Pharmaceuticals and personal care products in the aquatic environment in China: a review
  publication-title: J. Hazard. Mater.
– year: 2019
  ident: bib0010
  article-title: Improvement of Guidance and Methods for the Identification and Assessment of PM/PMT Substances; FKZ 3716 67 416 0
– volume: 135
  start-page: 236
  year: 2017
  end-page: 242
  ident: bib0210
  article-title: Occurrence and risk assessment of antibiotics in surface water and groundwater from different depths of aquifers: a case study at Jianghan Plain, central China
  publication-title: Ecotoxicol. Environ. Saf.
– reference: ChemAxon; ChemAxon:
– volume: 236
  start-page: 889
  year: 2018
  end-page: 898
  ident: bib0215
  article-title: Occurrence and indicators of pharmaceuticals in Chinese streams: a nationwide study
  publication-title: Environ. Pollut.
– year: 2018
  ident: bib0125
  article-title: National Action Plan for Environmental Protection of Centralized Drinking Water Sources; 000014672/2018-00402
– volume: 26
  start-page: 28796
  year: 2019
  end-page: 28807
  ident: bib0190
  article-title: Occurrence and ecological risk of pharmaceutical and personal care products in surface water of the Dongting Lake, China-during rainstorm period
  publication-title: Environ. Sci. Pollut. Res.
– volume: 32
  start-page: 155
  year: 2020
  ident: bib0085
  article-title: Persistent, mobile and toxic (PMT) and very persistent and very mobile (vPvM) substances pose an equivalent level of concern to persistent, bioaccumulative and toxic (PBT) and very persistent and very bioaccumulative (vPvB) substances under REACH
  publication-title: Environ. Sci. Eur.
– volume: 589
  start-page: 46
  year: 2017
  end-page: 55
  ident: bib0150
  article-title: Occurrence and ecological risk assessment of emerging organic chemicals in urban rivers: Guangzhou as a case study in China
  publication-title: Sci. Total Environ.
– volume: 54
  start-page: 7398
  year: 2020
  end-page: 7408
  ident: bib0225
  article-title: Screening new persistent and bioaccumulative organics in China’s inventory of industrial chemicals
  publication-title: Environ. Sci. Technol.
– volume: 490
  start-page: 889
  year: 2014
  end-page: 898
  ident: bib0145
  article-title: Occurrence and ecological potential of pharmaceuticals and personal care products in groundwater and reservoirs in the vicinity of municipal landfills in China
  publication-title: Sci. Total Environ.
– volume: 175
  year: 2020
  ident: bib0020
  article-title: Efficient detection and assessment of human exposure to trace antibiotic residues in drinking water
  publication-title: Water Res.
– volume: 185
  year: 2020
  ident: bib0070
  article-title: Distribution and human health risk assessment of antibiotic residues in large-scale drinking water sources in Chongqing area of the Yangtze River
  publication-title: Environ. Res.
– year: 2020
  ident: bib0090
  article-title: EnviroTox - Tools for Calculating Ecotoxicological Thresholds of Concern
– year: 2020
  ident: bib0095
  article-title: The need to adopt an international PMT strategy to protect drinking water resources
  publication-title: Environ. Sci. Technol.
– volume: 6
  start-page: 34928
  year: 2016
  ident: bib0230
  article-title: Occurrence and preliminarily environmental risk assessment of selected pharmaceuticals in the urban rivers
  publication-title: China. Sci. Rep.
– volume: 262
  start-page: 189
  year: 2013
  ident: 10.1016/j.hazl.2021.100026_bib0025
  article-title: Pharmaceuticals and personal care products in the aquatic environment in China: a review
  publication-title: J. Hazard. Mater.
  doi: 10.1016/j.jhazmat.2013.08.040
– volume: 720
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0170
  article-title: Endocrine disrupting compounds, pharmaceuticals and personal care products in the aquatic environment of China: which chemicals are the prioritized ones?
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2020.137652
– ident: 10.1016/j.hazl.2021.100026_bib0180
– volume: 32
  start-page: 155
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0085
  article-title: Persistent, mobile and toxic (PMT) and very persistent and very mobile (vPvM) substances pose an equivalent level of concern to persistent, bioaccumulative and toxic (PBT) and very persistent and very bioaccumulative (vPvB) substances under REACH
  publication-title: Environ. Sci. Eur.
  doi: 10.1186/s12302-020-00440-4
– volume: 136
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0115
  article-title: Ecological risk assessment of fifty pharmaceuticals and personal care products (PPCPs) in Chinese surface waters: a proposed multiple-level system
  publication-title: Environ. Int.
  doi: 10.1016/j.envint.2019.105454
– year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0090
– volume: 54
  start-page: 7398
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0225
  article-title: Screening new persistent and bioaccumulative organics in China’s inventory of industrial chemicals
  publication-title: Environ. Sci. Technol.
  doi: 10.1021/acs.est.0c01898
– volume: 152
  start-page: 1
  year: 2016
  ident: 10.1016/j.hazl.2021.100026_bib0110
  article-title: Occurrence, removal and risk assessment of pharmaceutical and personal care products (PPCPs) in an advanced drinking water treatment plant (ADWTP) around Taihu Lake in China
  publication-title: Chemosphere
  doi: 10.1016/j.chemosphere.2016.02.109
– year: 2019
  ident: 10.1016/j.hazl.2021.100026_bib0130
– volume: 236
  start-page: 889
  year: 2018
  ident: 10.1016/j.hazl.2021.100026_bib0215
  article-title: Occurrence and indicators of pharmaceuticals in Chinese streams: a nationwide study
  publication-title: Environ. Pollut.
  doi: 10.1016/j.envpol.2017.10.032
– volume: 50
  start-page: 10308
  year: 2016
  ident: 10.1016/j.hazl.2021.100026_bib0160
  article-title: Mind the gap: persistent and mobile organic compounds—water contaminants that slip through
  publication-title: Environ. Sci. Technol.
  doi: 10.1021/acs.est.6b03338
– year: 2017
  ident: 10.1016/j.hazl.2021.100026_bib0065
– year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0095
  article-title: The need to adopt an international PMT strategy to protect drinking water resources
  publication-title: Environ. Sci. Technol.
  doi: 10.1021/acs.est.0c04281
– ident: 10.1016/j.hazl.2021.100026_bib0140
– volume: 54
  start-page: 2575
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0195
  article-title: Toward a global understanding of chemical pollution: a first comprehensive analysis of national and regional chemical inventories
  publication-title: Environ. Sci. Technol.
  doi: 10.1021/acs.est.9b06379
– volume: 49
  start-page: 6772
  year: 2015
  ident: 10.1016/j.hazl.2021.100026_bib0220
  article-title: Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling, and linkage to bacterial resistance
  publication-title: Environ. Sci. Technol.
  doi: 10.1021/acs.est.5b00729
– volume: 26
  start-page: 28796
  year: 2019
  ident: 10.1016/j.hazl.2021.100026_bib0190
  article-title: Occurrence and ecological risk of pharmaceutical and personal care products in surface water of the Dongting Lake, China-during rainstorm period
  publication-title: Environ. Sci. Pollut. Res.
  doi: 10.1007/s11356-019-06047-4
– ident: 10.1016/j.hazl.2021.100026_bib0135
– volume: 135
  start-page: 236
  year: 2017
  ident: 10.1016/j.hazl.2021.100026_bib0210
  article-title: Occurrence and risk assessment of antibiotics in surface water and groundwater from different depths of aquifers: a case study at Jianghan Plain, central China
  publication-title: Ecotoxicol. Environ. Saf.
  doi: 10.1016/j.ecoenv.2016.10.006
– year: 2019
  ident: 10.1016/j.hazl.2021.100026_bib0010
– year: 2018
  ident: 10.1016/j.hazl.2021.100026_bib0125
– volume: 609
  start-page: 1423
  year: 2017
  ident: 10.1016/j.hazl.2021.100026_bib0185
  article-title: Occurrence and ecological hazard assessment of selected antibiotics in the surface waters in and around Lake Honghu, China
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2017.08.009
– volume: 135
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0205
  article-title: Anthropogenic impacts on the contamination of pharmaceuticals and personal care products (PPCPs) in the coastal environments of the Yellow and Bohai seas
  publication-title: Environ. Int.
  doi: 10.1016/j.envint.2019.105306
– volume: 75
  start-page: 1202
  year: 2016
  ident: 10.1016/j.hazl.2021.100026_bib0045
  article-title: Antibiotics in water and sediments from Liao River in Jilin Province, China: occurrence, distribution, and risk assessment
  publication-title: Environ. Earth Sci.
  doi: 10.1007/s12665-016-6008-4
– volume: 36
  start-page: 167
  year: 2016
  ident: 10.1016/j.hazl.2021.100026_bib0035
  article-title: Occurrence and partitioning of antibiotics in the water column and bottom sediments from the intertidal zone in the Bohai Bay, China
  publication-title: Wetlands
  doi: 10.1007/s13157-014-0561-y
– year: 2005
  ident: 10.1016/j.hazl.2021.100026_bib0005
– ident: 10.1016/j.hazl.2021.100026_bib0055
– volume: 183
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0040
  article-title: Advancements in effect-based surface water quality assessment
  publication-title: Water Res.
  doi: 10.1016/j.watres.2020.116017
– volume: 175
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0020
  article-title: Efficient detection and assessment of human exposure to trace antibiotic residues in drinking water
  publication-title: Water Res.
  doi: 10.1016/j.watres.2020.115699
– ident: 10.1016/j.hazl.2021.100026_bib0030
– volume: 589
  start-page: 46
  year: 2017
  ident: 10.1016/j.hazl.2021.100026_bib0150
  article-title: Occurrence and ecological risk assessment of emerging organic chemicals in urban rivers: Guangzhou as a case study in China
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2017.02.200
– volume: 185
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0070
  article-title: Distribution and human health risk assessment of antibiotic residues in large-scale drinking water sources in Chongqing area of the Yangtze River
  publication-title: Environ. Res.
  doi: 10.1016/j.envres.2020.109386
– volume: 490
  start-page: 889
  year: 2014
  ident: 10.1016/j.hazl.2021.100026_bib0145
  article-title: Occurrence and ecological potential of pharmaceuticals and personal care products in groundwater and reservoirs in the vicinity of municipal landfills in China
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2014.05.068
– volume: 72
  start-page: 3
  year: 2015
  ident: 10.1016/j.hazl.2021.100026_bib0155
  article-title: A review on emerging contaminants in wastewaters and the environment: current knowledge, understudied areas and recommendations for future monitoring
  publication-title: Water Res.
  doi: 10.1016/j.watres.2014.08.053
– volume: 133
  start-page: 182
  year: 2018
  ident: 10.1016/j.hazl.2021.100026_bib0175
  article-title: Occurrence and fate of emerging contaminants in municipal wastewater treatment plants from different geographical regions-a review
  publication-title: Water Res.
  doi: 10.1016/j.watres.2017.12.029
– year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0060
– volume: 46
  start-page: 5680
  year: 2012
  ident: 10.1016/j.hazl.2021.100026_bib0165
  article-title: Screening for PBT chemicals among the “Existing” and “New” chemicals of the EU
  publication-title: Environ. Sci. Technol.
  doi: 10.1021/es3002713
– volume: 253
  year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0105
  article-title: Prioritization of pharmaceuticals in water environment in China based on environmental criteria and risk analysis of top-priority pharmaceuticals
  publication-title: J. Environ. Manage.
  doi: 10.1016/j.jenvman.2019.109732
– volume: 19
  start-page: 939
  year: 2017
  ident: 10.1016/j.hazl.2021.100026_bib0015
  article-title: Ranking REACH registered neutral, ionizable and ionic organic chemicals based on their aquatic persistency and mobility
  publication-title: Environ. Sci. Process. Impacts
  doi: 10.1039/C7EM00158D
– volume: 17
  start-page: 477
  year: 2019
  ident: 10.1016/j.hazl.2021.100026_bib0120
  article-title: Occurrence and distribution of pharmaceuticals in raw, finished, and drinking water from seven large river basins in China
  publication-title: J. Water Health
  doi: 10.2166/wh.2019.250
– year: 2020
  ident: 10.1016/j.hazl.2021.100026_bib0080
  article-title: What’s in a name: Persistent, Mobile, and Toxic (PMT) and Very Persistent and Very Mobile (vPvM) substances
  publication-title: Environ. Sci. Technol.
  doi: 10.1021/acs.est.0c05257
– volume: 24
  start-page: 15838
  year: 2017
  ident: 10.1016/j.hazl.2021.100026_bib0200
  article-title: Occurrence, distribution, and attenuation of pharmaceuticals and personal care products in the riverside groundwater of the Beiyun River of Beijing, China
  publication-title: Environ. Sci. Pollut. Res.
  doi: 10.1007/s11356-017-8999-0
– year: 2019
  ident: 10.1016/j.hazl.2021.100026_bib0075
– volume: 696
  year: 2019
  ident: 10.1016/j.hazl.2021.100026_bib0100
  article-title: Occurrence and ranking of pharmaceuticals in the major rivers of China
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2019.133991
– volume: 595
  start-page: 521
  year: 2017
  ident: 10.1016/j.hazl.2021.100026_bib0050
  article-title: Antibiotics in the coastal water of the South Yellow Sea in China: occurrence, distribution and ecological risks
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2017.03.281
– volume: 18
  start-page: 500
  year: 2016
  ident: 10.1016/j.hazl.2021.100026_bib0235
  article-title: Occurrence, spatiotemporal distribution, mass balance and ecological risks of antibiotics in subtropical shallow Lake Taihu, China
  publication-title: Environ. Sci. Process. Impacts
  doi: 10.1039/C6EM00062B
– volume: 6
  start-page: 34928
  year: 2016
  ident: 10.1016/j.hazl.2021.100026_bib0230
  article-title: Occurrence and preliminarily environmental risk assessment of selected pharmaceuticals in the urban rivers
  publication-title: China. Sci. Rep.
  doi: 10.1038/srep34928
SSID ssj0002811330
Score 2.400506
Snippet [Display omitted] •First PMT assessment for over 400 pharmaceuticals and personal care products (PPCPs).•Compilation of PPCPs in Chinese surface water,...
Hazard classifications have recently been introduced for persistent, mobile and toxic (PMT) and very persistent and very mobile (vPvM) substances, which are...
SourceID doaj
crossref
elsevier
SourceType Open Website
Enrichment Source
Index Database
Publisher
StartPage 100026
SubjectTerms Drinking water
Groundwater
PPCP
Surface water
vPvM
Title The distribution of persistent, mobile and toxic (PMT) pharmaceuticals and personal care products monitored across Chinese water resources
URI https://dx.doi.org/10.1016/j.hazl.2021.100026
https://doaj.org/article/a2dd41fece6949b586c5152c50fb75c7
Volume 2
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3NS8MwFA_iyYsoKs4vcvCgaLFdk3Q5qmyIMPGwwW4lzQcq2pWtonjwD_Cv9r0mGz3Ni5dS2jQJeS_8fnl9H4ScGkQRwWzkjLYRnL9kpCQQuVgimErJlcB45-GDuBuz-wmftEp9oU-YTw_sF-5KdY1hibPaCslkwXtCAwR3NY9dkXHdxJED5rUOUy-NySiBwxcaWACABO7oOETMeOeuJ_WF_x26CXoJNJkVWqjUJO9vgVMLcAZbZDMwRXrtZ7hN1my5Q35ArNRgsttQp4pOHa3Q5gXSKutL-jYtYJ9TVRpaTz-fNT17HI7OafXUNl3Pm_dV4OEUvb9o5VO_zqEH3OUza6hqJkuxxLadW_oBtHRGZ8HeP98l40F_dHsXhXIKkWZJXEcamFbGjDQpsIasSI1IhbA9GwMFU9Jwl8FNljkulcEAa1g0o1PLtXVMusSme2S9nJZ2n1AVC8V1T1qTKeYMcBzVA16QJk4AQ2BZhySL5cx1yDWOJS9e84VT2UuOIshRBLkXQYdcLL-pfKaNla1vUErLlpglu3kAupMH3cn_0p0O4QsZ54FweCIBXT2vGPzgPwY_JBvYpY9rPCLr9ezdHgPBqYuTRpfhOvzu_wIjFvkM
linkProvider Directory of Open Access Journals
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+distribution+of+persistent%2C+mobile+and+toxic+%28PMT%29+pharmaceuticals+and+personal+care+products+monitored+across+Chinese+water+resources&rft.jtitle=Journal+of+hazardous+materials+letters&rft.au=Huang%2C+Chen&rft.au=Jin%2C+Biao&rft.au=Han%2C+Min&rft.au=Yu%2C+Yang&rft.date=2021-11-01&rft.pub=Elsevier+B.V&rft.issn=2666-9110&rft.eissn=2666-9110&rft.volume=2&rft_id=info:doi/10.1016%2Fj.hazl.2021.100026&rft.externalDocID=S2666911021000149
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2666-9110&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2666-9110&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2666-9110&client=summon