Microfiltration of concentrated albumin solutions and the role of processing conditions on membrane fouling

• Published in: Chemical engineering journal advances Vol. 16; p. 100561
• Main Authors: Cirillo, Andrea Iginio, Tomaiuolo, Giovanna, Guido, Stefano
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.11.2023; Elsevier
• Subjects: Bovine serum albumin (BSA); Membrane fouling; Microfiltration; Miniaturization; Pumping system; Residence time; Microfiltration; Bovine serum albumin (BSA); Pumping system; Miniaturization; Residence time; Membrane fouling

•A novel miniaturized filtration module was developed to study membrane fouling.•Lower fouling propensity was found for crossflow (CF) with a peristaltic pump.•The performances of peristaltic CF are related to reduced albumin residence time.•A cake layer at lower TMP and larger membrane pore size fo...