Approach to and treatment of goiters
The main causes of simple diffuse goiter (SDG) and multinodular goiter (MNG) are iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, chronic malnutrition, and lack of selenium, iron, and zinc. Increasing evidence suggests that heredity is equall...
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Published in | The Medical clinics of North America Vol. 96; no. 2; p. 351 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
01.03.2012
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Abstract | The main causes of simple diffuse goiter (SDG) and multinodular goiter (MNG) are iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, chronic malnutrition, and lack of selenium, iron, and zinc. Increasing evidence suggests that heredity is equally important. Treatment of SDG and MNG still focuses on L-thyroxine-suppressive therapy surgery. Radioiodine alone or preceded by recombinant human TSH stimulation is widely used in Europe and other countries. Each of these therapeutic options has advantages and disadvantages, with acute and long-term side effects. |
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AbstractList | The main causes of simple diffuse goiter (SDG) and multinodular goiter (MNG) are iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, chronic malnutrition, and lack of selenium, iron, and zinc. Increasing evidence suggests that heredity is equally important. Treatment of SDG and MNG still focuses on L-thyroxine-suppressive therapy surgery. Radioiodine alone or preceded by recombinant human TSH stimulation is widely used in Europe and other countries. Each of these therapeutic options has advantages and disadvantages, with acute and long-term side effects. |
Author | Medeiros-Neto, Geraldo Camargo, Rosalinda Y Tomimori, Eduardo K |
Author_xml | – sequence: 1 givenname: Geraldo surname: Medeiros-Neto fullname: Medeiros-Neto, Geraldo email: medneto@uol.com.br organization: Division of Endocrinology, Department of Medicine, University of Sao Paulo Medical School, Rua Artur Ramos, 96 - 5A, 01454-903 Sao Paulo, Brazil. medneto@uol.com.br – sequence: 2 givenname: Rosalinda Y surname: Camargo fullname: Camargo, Rosalinda Y – sequence: 3 givenname: Eduardo K surname: Tomimori fullname: Tomimori, Eduardo K |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22443980$$D View this record in MEDLINE/PubMed |
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SubjectTerms | Combined Modality Therapy Goiter - prevention & control Goiter - therapy Goiter, Nodular - therapy Humans Iodine Radioisotopes - therapeutic use Risk Factors Thyroidectomy - methods Thyrotropin - therapeutic use Thyroxine - therapeutic use |
Title | Approach to and treatment of goiters |
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