Approach to and treatment of goiters

The main causes of simple diffuse goiter (SDG) and multinodular goiter (MNG) are iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, chronic malnutrition, and lack of selenium, iron, and zinc. Increasing evidence suggests that heredity is equall...

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Bibliographic Details
Published inThe Medical clinics of North America Vol. 96; no. 2; p. 351
Main Authors Medeiros-Neto, Geraldo, Camargo, Rosalinda Y, Tomimori, Eduardo K
Format Journal Article
LanguageEnglish
Published United States 01.03.2012
Subjects
Combined Modality Therapy
Goiter - prevention & control
Goiter - therapy
Goiter, Nodular - therapy
Humans
Iodine Radioisotopes - therapeutic use
Risk Factors
Thyroidectomy - methods
Thyrotropin - therapeutic use
Thyroxine - therapeutic use
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Summary:The main causes of simple diffuse goiter (SDG) and multinodular goiter (MNG) are iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, chronic malnutrition, and lack of selenium, iron, and zinc. Increasing evidence suggests that heredity is equally important. Treatment of SDG and MNG still focuses on L-thyroxine-suppressive therapy surgery. Radioiodine alone or preceded by recombinant human TSH stimulation is widely used in Europe and other countries. Each of these therapeutic options has advantages and disadvantages, with acute and long-term side effects.
ISSN:1557-9859
DOI:10.1016/j.mcna.2012.01.010