Advances in the scaffolds fabrication techniques using biocompatible polymers and their biomedical application: A technical and statistical review
With the advancement in tissue engineering, researchers are working hard on new techniques to fabricate more advanced scaffolds from biocompatible polymers with enhanced porosity, appropriate mechanical strength, diverse shapes and sizes for potential applications in biomedical field in general and...
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| Published in | Journal of Saudi Chemical Society Vol. 24; no. 2; pp. 186 - 215 |
|---|---|
| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier B.V
01.02.2020
Springer |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1319-6103 |
| DOI | 10.1016/j.jscs.2020.01.002 |
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| Abstract | With the advancement in tissue engineering, researchers are working hard on new techniques to fabricate more advanced scaffolds from biocompatible polymers with enhanced porosity, appropriate mechanical strength, diverse shapes and sizes for potential applications in biomedical field in general and tissue engineering in particular. These techniques include electrospinning, solution blow spinning, centrifugal spinning, particulate leaching (salt leaching), freeze-drying, lithography, self-assembly, phase separation, gas foaming, melt molding, 3-D printing, fiber mesh and solvent casting. In this article we have summarized the scaffold’s fabrication techniques from biocompatible polymers that are reported so far, the recent advances in these techniques, characterization of the physicochemical properties of scaffolds and their potential applications in the biomedical field and tissue engineering. The article will help both newcomers and experts working in the biomedical implant fabrication to not only find their desired information in one document but also understand the fabrication techniques and the parameters that control the success of biocompatible polymeric scaffolds. Furthermore, a static analysis of the work published in all forms on the most innovative techniques is also presented. The data is taken from Scopus, restricting the search to biomedical fields and tissue engineering. |
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| AbstractList | With the advancement in tissue engineering, researchers are working hard on new techniques to fabricate more advanced scaffolds from biocompatible polymers with enhanced porosity, appropriate mechanical strength, diverse shapes and sizes for potential applications in biomedical field in general and tissue engineering in particular. These techniques include electrospinning, solution blow spinning, centrifugal spinning, particulate leaching (salt leaching), freeze-drying, lithography, self-assembly, phase separation, gas foaming, melt molding, 3-D printing, fiber mesh and solvent casting. In this article we have summarized the scaffold’s fabrication techniques from biocompatible polymers that are reported so far, the recent advances in these techniques, characterization of the physicochemical properties of scaffolds and their potential applications in the biomedical field and tissue engineering. The article will help both newcomers and experts working in the biomedical implant fabrication to not only find their desired information in one document but also understand the fabrication techniques and the parameters that control the success of biocompatible polymeric scaffolds. Furthermore, a static analysis of the work published in all forms on the most innovative techniques is also presented. The data is taken from Scopus, restricting the search to biomedical fields and tissue engineering. With the advancement in tissue engineering, researchers are working hard on new techniques to fabricate more advanced scaffolds from biocompatible polymers with enhanced porosity, appropriate mechanical strength, diverse shapes and sizes for potential applications in biomedical field in general and tissue engineering in particular. These techniques include electrospinning, solution blow spinning, centrifugal spinning, particulate leaching (salt leaching), freeze-drying, lithography, self-assembly, phase separation, gas foaming, melt molding, 3-D printing, fiber mesh and solvent casting. In this article we have summarized the scaffold’s fabrication techniques from biocompatible polymers that are reported so far, the recent advances in these techniques, characterization of the physicochemical properties of scaffolds and their potential applications in the biomedical field and tissue engineering. The article will help both newcomers and experts working in the biomedical implant fabrication to not only find their desired information in one document but also understand the fabrication techniques and the parameters that control the success of biocompatible polymeric scaffolds. Furthermore, a static analysis of the work published in all forms on the most innovative techniques is also presented. The data is taken from Scopus, restricting the search to biomedical fields and tissue engineering. Keywords: Biocompatible polymeric Scaffolds, Scaffolds fabrication techniques, Tissue engineering, Biomedical application |
| Author | Rao Kummara, Madhusudana Soo Han, Sung Alghyamah, Abdul-Aziz A Amjid Afridi, Mohammad Haider, Sajjad Khan, Naeem Alrahlah, Ali Jan Iftikhar, Faiza Bano, Bushra Haider, Adnan Khan, Rawaiz Kamal, Tahseen |
| Author_xml | – sequence: 1 givenname: Adnan surname: Haider fullname: Haider, Adnan organization: Department of Chemistry, Kohat University of Science and Technology, Kohat 26000, KP, Pakistan – sequence: 2 givenname: Sajjad surname: Haider fullname: Haider, Sajjad email: shaider@ksu.edu.sa organization: Department of Chemical Engineering, College of Engineering, King Saud University, P.O BOX 800, Riyadh 11421, KSA, Saudi Arabia – sequence: 3 givenname: Madhusudana surname: Rao Kummara fullname: Rao Kummara, Madhusudana organization: Department of Nano, Medical and Polymer Materials, College of Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, South Korea – sequence: 4 givenname: Tahseen surname: Kamal fullname: Kamal, Tahseen organization: Department of Chemistry, Faculty of Science, King Abdul Aziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia – sequence: 5 givenname: Abdul-Aziz A surname: Alghyamah fullname: Alghyamah, Abdul-Aziz A organization: Department of Chemical Engineering, College of Engineering, King Saud University, P.O BOX 800, Riyadh 11421, KSA, Saudi Arabia – sequence: 6 givenname: Faiza surname: Jan Iftikhar fullname: Jan Iftikhar, Faiza organization: Department of Chemistry, Quaid Azam University, Islamabad, Pakistan – sequence: 7 givenname: Bushra surname: Bano fullname: Bano, Bushra organization: Institute of Basic Medical Science, Khyber Medical University, Peshawar, KP, Pakistan – sequence: 8 givenname: Naeem surname: Khan fullname: Khan, Naeem organization: Department of Chemistry, Kohat University of Science and Technology, Kohat 26000, KP, Pakistan – sequence: 9 givenname: Mohammad surname: Amjid Afridi fullname: Amjid Afridi, Mohammad organization: Department of Pathology, Gajju Khan Medical College, Swab, KP, Pakistan – sequence: 10 givenname: Sung surname: Soo Han fullname: Soo Han, Sung email: sshan@yu.ac.kr organization: Department of Nano, Medical and Polymer Materials, College of Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, South Korea – sequence: 11 givenname: Ali surname: Alrahlah fullname: Alrahlah, Ali organization: Engineer Abdullah Bugshan Research Chair for Dental and Oral Rehabilitation, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia – sequence: 12 givenname: Rawaiz surname: Khan fullname: Khan, Rawaiz organization: Engineer Abdullah Bugshan Research Chair for Dental and Oral Rehabilitation, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia |
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| Keywords | PCLEEP PEU SLA PCLA UC PLDLA-AAc PELA HFP Tg PLLA-TMC TIPS PBS FGF HGF POE μCP LIFT PGA LOM RGD PCA DCM μm MAG 1D PLDLA PCL SEM PGS PLCL PPC PLA hMSC HDFs CJP AFM DLP AJS SMCs nHA-I PPL FDM PHBHV EBM 2D SFF THF PLLA FTIR TGF-α PLT DMD XPS DMF Biocompatible polymeric Scaffolds LENS Nm SFT SLS/SLM BMP EGF Tissue engineering nHA VEGF PEGDA IGF Scaffolds fabrication techniques EVOH ECM rpm HEMA NIL BET 3D FAK PLGA PEG PMMA PE DNA PDGF Biomedical application HA PVA PPF-PLLA PAM |
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