Comparison of 5 Different Remifentanil Strategies Against Myocardial Ischemia-Reperfusion Injury

• Published in: Journal of cardiothoracic and vascular anesthesia Vol. 25; no. 6; pp. 926 - 930
• Main Authors: Chun, Kook Jin, MD, PhD, Park, Yong Hyun, MD, PhD, Kim, Jeong Su, MD, Jang, Youngho, MD, PhD, Kim, June Hong, MD, PhD, Kim, Jun, MD, PhD, Lee, Mi Young, MD, PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2011
• Subjects: Anesthesia & Perioperative Care; Anesthetics, Intravenous - administration & dosage; Anesthetics, Intravenous - pharmacology; Animals; Body Weight - physiology; cardiodynamics; Cardiotonic Agents; Coloring Agents; Coronary Circulation - physiology; Critical Care; Heart - drug effects; Heart Function Tests; In Vitro Techniques; Ischemic Postconditioning - methods; Ischemic Preconditioning, Myocardial - methods; Male; Myocardial Infarction - pathology; Myocardial Infarction - prevention & control; myocardial ischemia; Myocardial Reperfusion Injury - prevention & control; Organ Size - physiology; Piperidines - administration & dosage; Piperidines - pharmacology; postconditioning; preconditioning; Rats; Rats, Sprague-Dawley; remifentanil; Reperfusion; Tetrazolium Salts; Ventricular Function, Left - physiology; postconditioning; myocardial ischemia; remifentanil; cardiodynamics; preconditioning

Objective The purpose of this study was to investigate the effects of various remifentanil strategies (preconditioning, postconditioning, or continuous infusion) against myocardial ischemia-reperfusion injury. Design An in vitro experimental study using the Langendorff system. Setting A university r...