Transcriptional investigation of the toxic mechanisms of perfluorooctane sulfonate in rats based on an RNA-Seq approach - Wang, Tianrun; Zhao, Xuying; Liu, Tianze; Zhang, Jiguang; Qiu, Jing; Li, Mei; Weng, Rui (Chemosphere (Oxford), 2023)
Keywords: Alkanesulfonic Acids - chemistry; animal models; Animals; B-lymphocytes; body weight changes; endoplasmic reticulum; Environmental Pollutants - metabolism; Environmental Pollutants - toxicity; Fluorocarbons - chemistry; genes; Hub genes; kidneys; liver; Liver - metabolism; metabolism; myeloid leukemia; perfluorooctane sulfonic acid; Persistent organic pollutants; PFOS; phagocytosis; protein-protein interactions; quantitative polymerase chain reaction; Rats; RNA-Seq; sequence analysis; Signalling pathway; spliceosomes; toxicity; transcription (genetics); transcriptomics; ultrastructure; Signalling pathway; Hub genes; Persistent organic pollutants; PFOS