Outcomes following surgical intervention for impending and gross instability caused by multiple myeloma in the spinal column

• Published in: Journal of neurosurgery. Spine Vol. 22; no. 3; p. 301
• Main Authors: Zadnik, Patricia L, Goodwin, C Rory, Karami, Kristophe J, Mehta, Ankit I, Amin, Anubhav G, Groves, Mari L, Wolinsky, Jean-Paul, Witham, Timothy F, Bydon, Ali, Gokaslan, Ziya L, Sciubba, Daniel M
• Format: Journal Article
• Language: English
• Published: United States 01.03.2015
• Subjects: Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Joint Instability - etiology; Joint Instability - surgery; Male; Middle Aged; Multiple Myeloma - surgery; Retrospective Studies; Spinal Neoplasms - surgery; Spine - pathology; Spine - surgery; Treatment Outcome; epidemiology; multiple myeloma; SR = sustained release; plasmacytoma; SINS = Spinal Instability Neoplastic Score; survival; IR = immediate release; spine; NSAID = nonsteroidal anti-inflammatory drug; oncology

Multiple myeloma is the most common primary tumor of the spine and is the most common primary malignant tumor of bone. Although spinal myeloma is classically a radiosensitive lesion, clinical or radiographic signs of instability merit surgical intervention. The authors present the epidemiology, surg...