Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods

Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that t...

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Published inJournal of Saudi Chemical Society Vol. 27; no. 3; p. 101628
Main Authors Pivazyan, Vergush A., Ghazaryan, Emma A., Karapetyan, Armen V., Shainova, Roza S., Harutyunyan, Siranush V., Vorskanyan, Asya S., Yengoyan, Aleksandr P., Gomktsyan, Tiruhi A.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.05.2023
Elsevier
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Abstract Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that the time of utrasound-promoted reactions was reduced by almost 6–96 times, and their yields were equal or turn out to be greater compared to the traditional approach. The synthesized compounds showed a pronounced stimulating effect on plant growth. The most active derivatives were selected for deeper biological studies and subsequent field trials.
AbstractList Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that the time of utrasound-promoted reactions was reduced by almost 6–96 times, and their yields were equal or turn out to be greater compared to the traditional approach. The synthesized compounds showed a pronounced stimulating effect on plant growth. The most active derivatives were selected for deeper biological studies and subsequent field trials.
ArticleNumber 101628
Author Karapetyan, Armen V.
Ghazaryan, Emma A.
Gomktsyan, Tiruhi A.
Pivazyan, Vergush A.
Vorskanyan, Asya S.
Harutyunyan, Siranush V.
Yengoyan, Aleksandr P.
Shainova, Roza S.
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Issue 3
Keywords Pyrimidine derivatives
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Plant growth stimulant activity
Sonochemical synthesis
Traditional synthesis
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g/ha
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Snippet Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by...
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SubjectTerms Plant growth stimulant activity
Pyrimidine derivatives
Sonochemical synthesis
Traditional synthesis
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Title Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods
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