Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods
Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that t...
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Published in | Journal of Saudi Chemical Society Vol. 27; no. 3; p. 101628 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
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Elsevier B.V
01.05.2023
Elsevier |
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Abstract | Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that the time of utrasound-promoted reactions was reduced by almost 6–96 times, and their yields were equal or turn out to be greater compared to the traditional approach. The synthesized compounds showed a pronounced stimulating effect on plant growth. The most active derivatives were selected for deeper biological studies and subsequent field trials. |
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AbstractList | Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that the time of utrasound-promoted reactions was reduced by almost 6–96 times, and their yields were equal or turn out to be greater compared to the traditional approach. The synthesized compounds showed a pronounced stimulating effect on plant growth. The most active derivatives were selected for deeper biological studies and subsequent field trials. |
ArticleNumber | 101628 |
Author | Karapetyan, Armen V. Ghazaryan, Emma A. Gomktsyan, Tiruhi A. Pivazyan, Vergush A. Vorskanyan, Asya S. Harutyunyan, Siranush V. Yengoyan, Aleksandr P. Shainova, Roza S. |
Author_xml | – sequence: 1 givenname: Vergush A. surname: Pivazyan fullname: Pivazyan, Vergush A. – sequence: 2 givenname: Emma A. surname: Ghazaryan fullname: Ghazaryan, Emma A. – sequence: 3 givenname: Armen V. surname: Karapetyan fullname: Karapetyan, Armen V. – sequence: 4 givenname: Roza S. surname: Shainova fullname: Shainova, Roza S. – sequence: 5 givenname: Siranush V. surname: Harutyunyan fullname: Harutyunyan, Siranush V. – sequence: 6 givenname: Asya S. surname: Vorskanyan fullname: Vorskanyan, Asya S. – sequence: 7 givenname: Aleksandr P. orcidid: 0000-0003-4411-4299 surname: Yengoyan fullname: Yengoyan, Aleksandr P. email: ayengoyan@mail.ru – sequence: 8 givenname: Tiruhi A. surname: Gomktsyan fullname: Gomktsyan, Tiruhi A. |
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CitedBy_id | crossref_primary_10_29328_journal_jpsp_1001126 |
Cites_doi | 10.1016/j.bmcl.2010.04.108 10.1016/j.ejmech.2009.09.039 10.1021/jm100568q 10.2478/v10007-010-0027-6 10.1016/j.ejmech.2006.09.012 10.1016/j.tet.2008.08.033 10.1016/j.bmc.2005.04.061 10.1016/j.bmc.2011.08.025 10.2174/156802612800229215 10.1021/jm011095y 10.1016/j.pbb.2005.08.003 10.2174/1573406411309050010 10.1016/j.ejmech.2017.02.024 10.1002/jhet.1585 10.1016/j.ejmech.2009.10.002 10.1016/j.bmc.2013.06.061 10.1007/s12272-010-0501-1 10.1016/j.bmcl.2014.04.079 10.1002/1521-4184(200208)335:6<289::AID-ARDP289>3.0.CO;2-Z 10.2174/1570178617999200601165334 10.3851/IMP1844 10.1002/jccs.201190056 10.1016/j.bmcl.2014.02.012 10.1016/j.ejmech.2014.10.061 10.1155/2017/8180913 10.1080/10426500701557286 |
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Keywords | Pyrimidine derivatives MW Plant growth stimulant activity Sonochemical synthesis Traditional synthesis US g/ha |
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Title | Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods |
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