Irisin is more strongly predicted by muscle oxidative potential than adiposity in non-diabetic men

• Published in: Journal of physiology and biochemistry Vol. 71; no. 3; pp. 559 - 568
• Main Authors: Huth, Claire, Dubois, Marie-Julie, Marette, André, Tremblay, Angelo, Weisnagel, S. John, Lacaille, Michel, Mauriège, Pascale, Joanisse, Denis R.
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.09.2015
• Subjects: Adiposity; Adult; Animal Physiology; Biomedical and Life Sciences; Biomedicine; Female; Fibronectins - blood; Human Physiology; Humans; Insulin Resistance; Male; Middle Aged; Mitochondria, Muscle - metabolism; Muscle, Skeletal - metabolism; Obesity - blood; Obesity - pathology; Original Paper; Oxidation-Reduction; Myokine; Irisin; Obesity; Adipose tissue; Adipokine; Insulin sensitivity

Numerous controversies surround the peptide hormone irisin. Although implicated as a myokine promoting the browning of adipose tissue in rodents, its roles in humans remain unclear. Contradictory results have also been found with respect to the relationships between adiposity or metabolic health and...