Use of a Multiplex Immunoassay Platform to Investigate Multifaceted Antibody Responses in SARS-CoV-2 Vaccinees with and Without Prior Infection

• Published in: COVID Vol. 5; no. 4; p. 44
• Main Authors: Odo, Troy, Haun, Brien K., Williams, Caitlin A., Ball, Aquena, To, Albert, Wong, Teri Ann S., Ching, Lauren, Nakano, Eileen, Van Ry, Alex, Pessaint, Laurent, Andersen, Hanne, Donini, Oreola, Nerurkar, Vivek R., Lehrer, Axel T.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.04.2025
• Subjects: humoral immunity; mRNA vaccine; multiplex immunoassay; multiplex inhibition test; SARS-CoV-2; subunit vaccine; avidity; multiplex immunoassay; SARS-CoV-2; humoral immunity; subunit vaccine; multiplex inhibition test; mRNA vaccine

The emergence of COVID-19 necessitated the rapid development of vaccines. While highly effective at reducing severe disease and death, breakthrough infections remain a problem as the virus continues to mutate. To help address this issue, we show the utility of a multiplex immunoassay in measuring mu...