Change Profiles and Functional Targets of MicroRNAs in Type 2 Diabetes Mellitus Patients with Obesity

• Published in: Diabetes & metabolism journal Vol. 47; no. 4; pp. 559 - 570
• Main Authors: Lu, Guanhua, Gao, Huanhuan, Dong, Zhiyong, Jiang, Shuwen, Hu, Ruixiang, Wang, Cunchuan
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Diabetes Association 01.07.2023
• Subjects: Bariatric Surgery; diabetes mellitus, type 2; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - genetics; Down-Regulation; Humans; metabolism; micrornas; MicroRNAs - genetics; obesity; Obesity - complications; Obesity - genetics; Original; Obesity; Diabetes mellitus, type 2; Metabolism; MicroRNAs; Bariatric surgery

MicroRNAs (miRNAs) exert an essential contribution to obesity and type 2 diabetes mellitus (T2DM). This study aimed to investigate the differences of miRNAs in the presence and absence of T2DM in patients with obesity, as well as before and after bariatric surgery in T2DM patients with obesity. Char...