Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration-QTc Relationships - Blanchette, Alexander D; Grimm, Fabian A; Dalaijamts, Chimeddulam; Hsieh, Nan-Hung; Ferguson, Kyle; Luo, Yu-Syuan; Rusyn, Ivan; Chiu, Weihsueh A (Clinical pharmacology and therapeutics, 2019)
Keywords: Cardiotoxins - analysis; Cardiotoxins - pharmacokinetics; Drug Evaluation, Preclinical - methods; Drug-Related Side Effects and Adverse Reactions - diagnosis; Humans; In Vitro Techniques - methods; Induced Pluripotent Stem Cells; Long QT Syndrome - chemically induced; Long QT Syndrome - diagnosis; Models, Cardiovascular; Myocytes, Cardiac - drug effects; Predictive Value of Tests