Polymerization‐Induced Self‐Assembly of Functionalized Block Copolymer Nanoparticles and Their Application in Drug Delivery

• Published in: Macromolecular rapid communications. Vol. 40; no. 2; pp. e1800279 - n/a
• Main Authors: Zhang, Wen‐Jian, Hong, Chun‐Yan, Pan, Cai‐Yuan
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.01.2019
• Subjects: Antibiotics, Antineoplastic - administration & dosage; Antibiotics, Antineoplastic - chemistry; Antibiotics, Antineoplastic - pharmacokinetics; Assembly; Block copolymers; Chemistry Techniques, Synthetic - methods; crosslinking; Doxorubicin - administration & dosage; Doxorubicin - chemistry; Doxorubicin - pharmacokinetics; Drug delivery; Drug delivery systems; Drug Delivery Systems - methods; Drug Liberation; Fabrication; Methacrylates - chemistry; Morphology; Nanoparticles; Nanoparticles - chemistry; Polymerization; polymerization‐induced self‐assembly; Polymers - chemical synthesis; Polymers - chemistry; Reproducibility; stimuli‐responsive polymers; stimuli-responsive polymers; polymerization-induced self-assembly; drug delivery; crosslinking

Drug delivery systems (DDS) based on functionalized polymeric nanoparticles have attracted considerable attention. Although great advances have been reported in the past decades, the fabrication efficiency and reproducibility of polymeric nanoparticles are barely satisfactory due to the intrinsic li...