Hydrogen Bonding‐Induced H‐Aggregation for Fluorescence Turn‐On of the GFP Chromophore: Supramolecular Structural Rigidity

• Published in: Chemistry : a European journal Vol. 26; no. 27; pp. 5942 - 5945
• Main Authors: Tsai, Meng‐Shiue, Tsai, Sung‐Yu, Huang, Yi‐Fan, Wang, Chien‐Lung, Sun, Shih‐Sheng, Yang, Jye‐Shane
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 12.05.2020; Wiley Subscription Services, Inc
• Subjects: Agglomeration; Aggregates; aggregation; Chemistry; Chemistry, Multidisciplinary; Chromophores; Fluorescence; gels; Hydrogen bonding; hydrogen bonds; Optoelectronics; Physical Sciences; Quantum efficiency; Rigidity; Science & Technology; supramolecular chemistry; ACTIVATION; fluorescence; gels; CYCLODEXTRIN; CONFINED CHROMOPHORES; EMISSION ENHANCEMENT; PHOTOPHYSICS; aggregation; hydrogen bonds; supramolecular chemistry

To turn on the fluorescence of the native green fluorescence protein (GFP) chromophore, 4‐hydroxybenzylidene‐dimethylimidazolinone (HBDI), in an artificial supramolecular system has been a challenging task, because it requires high local environmental rigidity. This work shows that the formation of...