A Supramolecular‐Based Dual‐Wavelength Phototherapeutic Agent with Broad‐Spectrum Antimicrobial Activity Against Drug‐Resistant Bacteria

• Published in: Angewandte Chemie International Edition Vol. 59; no. 9; pp. 3658 - 3664
• Main Authors: Yu, Zhi‐Hao, Li, Xingshu, Xu, Fugui, Hu, Xi‐Le, Yan, Jiatao, Kwon, Nahyun, Chen, Guo‐Rong, Tang, Tingting, Dong, Xiaojing, Mai, Yiyong, Chen, Daijie, Yoon, Juyoung, He, Xiao‐Peng, Tian, He
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 24.02.2020
• Edition: International ed. in English
• Subjects: Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Antibiotic resistance; Antibiotics; Antiinfectives and antibacterials; Antimicrobial activity; Antimicrobial agents; Bacteria; Drug resistance; Drug Resistance, Bacterial - drug effects; Gram-Negative Bacteria - drug effects; Graphene; graphene nanoribbons; Graphite - chemistry; In vivo methods and tests; Irradiation; Light; Light irradiation; Methicillin-Resistant Staphylococcus aureus - drug effects; Nanocomposites; Nanocomposites - chemistry; Nanocomposites - toxicity; Nanoparticles; Nanotubes - chemistry; Photodynamic therapy; phototherapy; Polyethylene Glycols - chemistry; porphyrin; Porphyrins - chemistry; Radiation; Reactive oxygen species; Reactive Oxygen Species - metabolism; Superstructures; supramolecular structures; phototherapy; porphyrin; antimicrobial activity; graphene nanoribbons; supramolecular structures

With the ever‐increasing threat posed by the multi‐drug resistance of bacteria, the development of non‐antibiotic agents for the broad‐spectrum eradication of clinically prevalent superbugs remains a global challenge. Here, we demonstrate the simple supramolecular self‐assembly of structurally defin...