The Effect of Theobromine Supplementation on HDL‐c Subclasses (HDL‐c2, HDL‐c3), HDL‐c2/HDL‐c3 Ratio, and Gene Expression of PPAR‐α and Sirt1 in Subjects With Metabolic Syndrome: A Randomized Controlled Clinical Trial - Sharifi‐Zahabi, Elham; Dastafkan, Zahra; Asadi, Amirhossein; Hosseini‐Baharanchi, Fatemeh Sadat; Rezvani, Nayebali; Yari, Saba; Shidfar, Farzad (Food science & nutrition, 2025)
Keywords: Antihypertensives; Apolipoproteins; Blood pressure; Body mass index; Caffeine; Calories; Cardiovascular disease; Cardiovascular diseases; Cholesterol; Clinical trials; Diabetes; Diet; Dietary intake; Dietary supplements; Exercise; Fatty acids; Food intake; Gene expression; Glucose; HDL‐c; Health risks; High density lipoprotein; Hypertension; Hypocaloric diet; Lipids; Lipoproteins; Metabolic disorders; Metabolic syndrome; Nutrient deficiency; Nutrition research; Original; Overweight; Oxidation; Peroxisome proliferator-activated receptors; Placebos; PPAR alpha; Risk factors; Serum levels; SIRT1 protein; Statins; Supplements; theobromine; Iran; metabolic syndrome; HDL‐c; PPAR alpha; theobromine