Propionic Acidemia‐Induced Proarrhythmic Electrophysiological Alterations in Human iPSC‐Derived Cardiomyocytes - Cámara‐Checa, Anabel; Álvarez, Mar; Rapún, Josu; Pérez‐Martín, Sara; Núñez‐Fernández, Roberto; Rubio‐Alarcón, Marcos; Crespo‐García, Teresa; Desviat, Lourdes R.; Delpón, Eva; Caballero, Ricardo; Richard, Eva (Journal of inherited metabolic disease, 2025)
Keywords: Action Potentials - physiology; Arrhythmia; Arrhythmias, Cardiac - etiology; Arrhythmias, Cardiac - metabolism; Arrhythmias, Cardiac - physiopathology; Calcium (intracellular); Calcium currents; Cardiac arrhythmia; Cardiomyocytes; Cardiomyopathy; Excitability; Heart; Humans; human‐induced pluripotent stem cell‐derived cardiomyocytes; Induced Pluripotent Stem Cells - cytology; Induced Pluripotent Stem Cells - metabolism; Ion currents; Latency; Membrane potential; Metabolic disorders; Methylmalonyl-CoA Decarboxylase - genetics; Mutation; Myocytes, Cardiac - metabolism; Myocytes, Cardiac - physiology; Na+/Ca2+ exchanger; Original; Patch-Clamp Techniques; patch‐clamp; Pluripotency; Propionic acidemia; Propionic Acidemia - complications; Propionic Acidemia - genetics; Propionic Acidemia - metabolism; Propionic Acidemia - physiopathology; human‐induced pluripotent stem cell‐derived cardiomyocytes; propionic acidemia; patch‐clamp; ion currents; heart