An introduction to DNA microarrays for gene expression analysis

• Published in: Chemometrics and intelligent laboratory systems Vol. 104; no. 1; pp. 28 - 52
• Main Authors: Karakach, Tobias K., Flight, Robert M., Douglas, Susan E., Wentzell, Peter D.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.11.2010
• Subjects: DNA microarray; Experimental design; Gene expression; GeneChip; DNA microarray; GeneChip; Gene expression; Experimental design

This tutorial presents a basic introduction to DNA microarrays as employed for gene expression analysis, approaching the subject from a chemometrics perspective. The emphasis is on describing the nature of the measurement process, from the platforms used to a few of the standard higher-level data an...