Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

• Published in: The journal of clinical endocrinology and metabolism Vol. 105; no. 4; pp. e1201 - e1214
• Main Authors: van der Spoel, Evie, Roelfsema, Ferdinand, Akintola, Abimbola A, Jansen, Steffy W, Slagboom, P Eline, Westendorp, Rudi G J, Blauw, Gerard J, Pijl, Hanno, van Heemst, Diana
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.04.2020
• Subjects: Adrenocorticotropic hormone; Aged; Aged, 80 and over; Aging; Biomarkers - blood; Circadian Rhythm; Confidence intervals; Cortisol; Entropy; Female; Follow-Up Studies; Growth hormones; Hormones; Human Growth Hormone - blood; Humans; Hydrocortisone - blood; Hypothalamus; Longevity; Male; Middle Aged; Online Only; Pituitary; Pituitary hormones; Pituitary Hormones - blood; Prognosis; cross-correlation; time series data; human; cross-approximate entropy; pituitary hormones; familial longevity

Abstract Context Hormones of the hypothalamic-pituitary-target gland axes are mostly investigated separately, whereas the interplay between hormones might be as important as each separate hormonal axis. Objective Our aim is to determine the interrelationships between GH, TSH, ACTH, and cortisol in h...