A STUDY OF THE CHANGES IN SERUM POTASSIUM CONCENTRATION WITH SUXAMETHONIUM USING DIFFERENT ANAESTHETIC AGENTS

Serum potassium concentrations were measured after administration of suxamethonium (1 mg\kg body wt.) in 101 patients in whom anaesthesia was induced by one of five different techniques. There was a maximum increase in serum potassium of 21.4% following induction with trichloroethylene compared with...

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Published inBritish journal of anaesthesia : BJA Vol. 47; no. 4; pp. 516 - 519
Main Authors DHANARAJ, V.J., NARAYANAMURTHY, J., SITADEVI, C., RAO, K. MOHAN
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.04.1975
Oxford University Press
Subjects
Adolescent
Adult
Aged
Anesthesia, General
Child
Child, Preschool
Chloroform
Ether
Female
Halothane
Humans
Male
Middle Aged
Nitrous Oxide
Oxygen
Potassium - blood
Succinylcholine - pharmacology
Thiopental
Trichloroethylene
Tubocurarine
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Summary:Serum potassium concentrations were measured after administration of suxamethonium (1 mg\kg body wt.) in 101 patients in whom anaesthesia was induced by one of five different techniques. There was a maximum increase in serum potassium of 21.4% following induction with trichloroethylene compared with 4.4% with nitrous oxide\oxygen. There were only small increaes in serum potassium with halothane and chloroform. In an additional 10 patients who received tubocurarine (3 mg) before induction of anaesthesia with thiopentone, the maximum increase in serum potassium was 10.6% following suxamethonium. It is concluded that the increase in serum potassium following induction of anaesthesia is the result of a combined effect of the anaesthetic agent and suxamethonium.
Bibliography:ark:/67375/HXZ-J535QV8Q-Z
ArticleID:47.4.516
istex:1F28AA92899F44E9474582AB2813E0D41E7AF759
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/47.4.516