Integrin signalling and traffic during axon growth and regeneration

• Published in: Current opinion in neurobiology Vol. 27; pp. 179 - 185
• Main Authors: Eva, Richard, Fawcett, James
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2014
• Subjects: Animals; Axons - metabolism; Integrins - metabolism; Nerve Regeneration - physiology; Neurology; Protein Transport - physiology; Psychiatry; Signal Transduction - physiology

•Integrins are subject to complex regulation by signalling and trafficking molecules.•Integrin activation occurs from inside and outside of the cell.•Integrins can mediate developmental CNS axon growth and axon regeneration in the PNS.•Activation of integrins can boost axon regeneration in the adult...