Is the Pandemic Wearing Us Out? A Cross-Sectional Study of the Prevalence of Fatigue in Adult Twins without Previous SARS-CoV-2 Infection
During the pandemic, mental health was not only impaired in people after a SARS-CoV-2 infection, but also in people without previous infection. This is the first study on twins without prior SARS-CoV-2 infection to estimate the influence of genetic components and shared as well as individual environ...
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Published in | Journal of clinical medicine Vol. 11; no. 23; p. 7067 |
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Language | English |
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29.11.2022
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Abstract | During the pandemic, mental health was not only impaired in people after a SARS-CoV-2 infection, but also in people without previous infection. This is the first study on twins without prior SARS-CoV-2 infection to estimate the influence of genetic components and shared as well as individual environments on pandemic-associated fatigue. The study sample included 55 monozygotic and 45 dizygotic twin pairs. A total of 34.5% reported an increase in fatigue since the pandemic. A significant correlation was shown between the responses within monozygotic (χ2[1] = 11.14, p = 0.001) and dizygotic pairs (χ2[1] = 18.72, p < 0.001). In all pandemic-associated fatigue dimensions, individual environment (ranging from e2 = 0.64 to e2 = 0.84) and heritability (ranging from h2 = 0.32 to h2 = 1.04) seem to have the highest impact. The number of comorbidities significantly correlated with physical fatigue (Spearman’s ρ = 0.232, p < 0.001) and psychological impairment due to pandemic measures with the total fatigue score (Spearman’s ρ = 0.243, p < 0.001). However, calculated ANCOVAs with these significant correlations as covariates showed no significant influence on the mean values of the respective fatigue dimensions. Susceptibility to pandemic-associated fatigue may be genetically and environmentally determined, while intensity is also influenced by individual components. The prevalence of fatigue is high even in individuals without prior SARS-CoV-2 infection. Future mental health prevention and intervention programs should be implemented to alleviate the impact of the pandemic on the global population. |
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AbstractList | During the pandemic, mental health was not only impaired in people after a SARS-CoV-2 infection, but also in people without previous infection. This is the first study on twins without prior SARS-CoV-2 infection to estimate the influence of genetic components and shared as well as individual environments on pandemic-associated fatigue. The study sample included 55 monozygotic and 45 dizygotic twin pairs. A total of 34.5% reported an increase in fatigue since the pandemic. A significant correlation was shown between the responses within monozygotic (χ2[1] = 11.14, p = 0.001) and dizygotic pairs (χ2[1] = 18.72, p < 0.001). In all pandemic-associated fatigue dimensions, individual environment (ranging from e2 = 0.64 to e2 = 0.84) and heritability (ranging from h2 = 0.32 to h2 = 1.04) seem to have the highest impact. The number of comorbidities significantly correlated with physical fatigue (Spearman’s ρ = 0.232, p < 0.001) and psychological impairment due to pandemic measures with the total fatigue score (Spearman’s ρ = 0.243, p < 0.001). However, calculated ANCOVAs with these significant correlations as covariates showed no significant influence on the mean values of the respective fatigue dimensions. Susceptibility to pandemic-associated fatigue may be genetically and environmentally determined, while intensity is also influenced by individual components. The prevalence of fatigue is high even in individuals without prior SARS-CoV-2 infection. Future mental health prevention and intervention programs should be implemented to alleviate the impact of the pandemic on the global population. During the pandemic, mental health was not only impaired in people after a SARS-CoV-2 infection, but also in people without previous infection. This is the first study on twins without prior SARS-CoV-2 infection to estimate the influence of genetic components and shared as well as individual environments on pandemic-associated fatigue. The study sample included 55 monozygotic and 45 dizygotic twin pairs. A total of 34.5% reported an increase in fatigue since the pandemic. A significant correlation was shown between the responses within monozygotic (χ 2 [1] = 11.14, p = 0.001) and dizygotic pairs (χ 2 [1] = 18.72, p < 0.001). In all pandemic-associated fatigue dimensions, individual environment (ranging from e 2 = 0.64 to e 2 = 0.84) and heritability (ranging from h 2 = 0.32 to h 2 = 1.04) seem to have the highest impact. The number of comorbidities significantly correlated with physical fatigue (Spearman’s ρ = 0.232, p < 0.001) and psychological impairment due to pandemic measures with the total fatigue score (Spearman’s ρ = 0.243, p < 0.001). However, calculated ANCOVAs with these significant correlations as covariates showed no significant influence on the mean values of the respective fatigue dimensions. Susceptibility to pandemic-associated fatigue may be genetically and environmentally determined, while intensity is also influenced by individual components. The prevalence of fatigue is high even in individuals without prior SARS-CoV-2 infection. Future mental health prevention and intervention programs should be implemented to alleviate the impact of the pandemic on the global population. |
Author | Stengel, Andreas Weimer, Katja Rupp, Sophia Kristina Goebel-Stengel, Miriam Enck, Paul Zipfel, Stephan |
AuthorAffiliation | 1 Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, 72076 Tübingen, Germany 4 Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany 3 Department of Internal Medicine, Helios Kliniken GmbH, 78628 Rottweil, Germany 2 Department of Psychosomatic Medicine and Psychotherapy, Ulm University Medical Center, 89081 Ulm, Germany |
AuthorAffiliation_xml | – name: 3 Department of Internal Medicine, Helios Kliniken GmbH, 78628 Rottweil, Germany – name: 1 Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, 72076 Tübingen, Germany – name: 2 Department of Psychosomatic Medicine and Psychotherapy, Ulm University Medical Center, 89081 Ulm, Germany – name: 4 Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany |
Author_xml | – sequence: 1 givenname: Sophia Kristina surname: Rupp fullname: Rupp, Sophia Kristina organization: Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, 72076 Tübingen, Germany – sequence: 2 givenname: Katja orcidid: 0000-0001-8656-607X surname: Weimer fullname: Weimer, Katja organization: Department of Psychosomatic Medicine and Psychotherapy, Ulm University Medical Center, 89081 Ulm, Germany – sequence: 3 givenname: Miriam surname: Goebel-Stengel fullname: Goebel-Stengel, Miriam organization: Department of Internal Medicine, Helios Kliniken GmbH, 78628 Rottweil, Germany – sequence: 4 givenname: Paul orcidid: 0000-0001-8873-0486 surname: Enck fullname: Enck, Paul organization: Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, 72076 Tübingen, Germany – sequence: 5 givenname: Stephan orcidid: 0000-0003-1659-4440 surname: Zipfel fullname: Zipfel, Stephan organization: Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, 72076 Tübingen, Germany – sequence: 6 givenname: Andreas surname: Stengel fullname: Stengel, Andreas organization: Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany |
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Cites_doi | 10.1371/journal.pgen.1010135 10.1016/j.autrev.2008.08.003 10.1017/thg.2020.85 10.1371/journal.pone.0237695 10.1017/S0033291798007934 10.1371/journal.pone.0198594 10.1007/s10072-020-04633-w 10.1037/0033-2909.83.5.762 10.1017/thg.2017.22 10.1016/j.psychres.2020.113003 10.1001/jamainternmed.2021.6454 10.1016/j.jad.2022.07.011 10.1148/radiol.2021211374 10.1037/1082-989X.1.1.30 10.1159/000319312 10.1111/j.1469-1809.1965.tb00500.x 10.1055/a-1544-8349 10.1371/journal.pone.0240784 10.3390/neurolint13030040 10.1016/0022-3999(94)00125-O 10.1515/znc-2022-0092 10.1017/S0033291705005222 10.1192/bjo.2022.506 10.1007/s00103-021-03400-2 10.1002/acn3.51350 10.1016/j.ssmmh.2022.100122 10.3389/fpsyt.2019.00679 10.1016/j.jpsychores.2017.06.013 10.1038/nrg932 10.1007/s11055-022-01222-6 10.1016/j.tmaid.2022.102430 10.1080/21642850.2022.2033121 10.3389/fpsyt.2022.947973 10.1038/s41598-022-12707-2 10.1016/j.psychres.2022.114678 10.1159/000069834 10.1016/j.ypmed.2021.106860 10.1007/s10519-021-10050-2 10.1371/journal.pone.0123992 10.1177/21501319221089255 10.1016/j.eujim.2021.101323 10.1097/00005650-199910000-00011 10.1037/1040-3590.6.4.284 10.1007/s12160-012-9463-5 10.1192/bjp.bp.109.069674 10.1016/S1473-3099(20)30114-6 10.3390/vaccines10040488 10.1097/RNJ.0000000000000278 10.1037/0033-2909.86.2.420 10.1016/j.psychres.2020.113699 10.1046/j.1365-2796.2002.01032.x |
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References | Bartko (ref_22) 1976; 83 ref_50 Matta (ref_5) 2022; 182 Stengel (ref_42) 2021; 71 Pelt (ref_10) 2021; 52 ref_11 Zolotovskaia (ref_33) 2022; 52 Wang (ref_35) 2021; 44 Sabaner (ref_54) 2022; 50 Schwarz (ref_32) 2003; 26 Corfield (ref_25) 2017; 20 Sullivan (ref_27) 2005; 35 ref_17 Hulme (ref_45) 2017; 99 Zhai (ref_56) 2020; 288 Boomsma (ref_6) 2002; 3 (ref_55) 2021; 77 ref_23 Bakalidou (ref_34) 2022; 14 ref_28 Zhang (ref_38) 2020; 42 Cicchetti (ref_21) 1994; 6 Augustin (ref_41) 2021; 6 Weimer (ref_15) 2019; 10 Graham (ref_43) 2021; 8 Ebinger (ref_51) 2021; 153 Lichtenstein (ref_16) 2002; 252 Ball (ref_29) 2010; 197 Rimfeld (ref_12) 2021; 51 Smets (ref_18) 1995; 39 Andelic (ref_30) 2022; 10 Poeschla (ref_59) 2013; 45 Tsang (ref_8) 2020; 296 Prasad (ref_49) 2021; 13 Torossian (ref_39) 2020; 46 Falconer (ref_24) 1965; 29 Lorusso (ref_44) 2009; 8 Queler (ref_53) 2022; 302 Hiller (ref_52) 2021; 13 McGraw (ref_20) 1996; 1 Farahi (ref_2) 2022; 315 Pandya (ref_1) 2022; 2 Shrout (ref_19) 1979; 86 Stephan (ref_58) 2022; 12 Williams (ref_31) 2020; 23 Gigantesco (ref_7) 2022; 314 ref_47 ref_46 Joli (ref_37) 2022; 13 ref_40 ref_3 Rimfeld (ref_13) 2022; 8 ref_48 ref_9 Enck (ref_14) 2021; 64 Pan (ref_57) 2020; 20 Hickie (ref_26) 1999; 29 ref_4 Bensing (ref_36) 1999; 37 Nater (ref_60) 2010; 79 |
References_xml | – ident: ref_11 doi: 10.1371/journal.pgen.1010135 – volume: 8 start-page: 287 year: 2009 ident: ref_44 article-title: Immunological aspects of chronic fatigue syndrome publication-title: Autoimmun. Rev. doi: 10.1016/j.autrev.2008.08.003 contributor: fullname: Lorusso – volume: 23 start-page: 316 year: 2020 ident: ref_31 article-title: Self-Reported Symptoms of COVID-19, Including Symptoms Most Predictive of SARS-CoV-2 Infection, Are Heritable publication-title: Twin Res. Hum. Genet. doi: 10.1017/thg.2020.85 contributor: fullname: Williams – ident: ref_9 doi: 10.1371/journal.pone.0237695 – volume: 29 start-page: 259 year: 1999 ident: ref_26 article-title: Unique genetic and environmental determinants of prolonged fatigue: A twin study publication-title: Psychol. Med. doi: 10.1017/S0033291798007934 contributor: fullname: Hickie – ident: ref_28 doi: 10.1371/journal.pone.0198594 – volume: 42 start-page: 1463 year: 2020 ident: ref_38 article-title: Related risk factors associated with post-stroke fatigue: A systematic review and meta-analysis publication-title: Neurol. Sci. doi: 10.1007/s10072-020-04633-w contributor: fullname: Zhang – volume: 83 start-page: 762 year: 1976 ident: ref_22 article-title: On various intraclass correlation reliability coefficients publication-title: Psychol. Bull. doi: 10.1037/0033-2909.83.5.762 contributor: fullname: Bartko – volume: 20 start-page: 208 year: 2017 ident: ref_25 article-title: Familiality and Heritability of Fatigue in an Australian Twin Sample publication-title: Twin Res. Hum. Genet. doi: 10.1017/thg.2017.22 contributor: fullname: Corfield – volume: 288 start-page: 113003 year: 2020 ident: ref_56 article-title: Addressing collegiate mental health amid COVID-19 pandemic publication-title: Psychiatry Res. doi: 10.1016/j.psychres.2020.113003 contributor: fullname: Zhai – volume: 182 start-page: 19 year: 2022 ident: ref_5 article-title: Association of Self-reported COVID-19 Infection and SARS-CoV-2 Serology Test Results With Persistent Physical Symptoms Among French Adults During the COVID-19 Pandemic publication-title: JAMA Intern. Med. doi: 10.1001/jamainternmed.2021.6454 contributor: fullname: Matta – volume: 315 start-page: 70 year: 2022 ident: ref_2 article-title: The global evolution of mental health problems during the COVID-19 pandemic: A systematic review and meta-analysis of longitudinal studies publication-title: J. Affect. Disord. doi: 10.1016/j.jad.2022.07.011 contributor: fullname: Farahi – volume: 302 start-page: 84 year: 2022 ident: ref_53 article-title: Parsonage-Turner Syndrome Following COVID-19 Vaccination: MR Neurography publication-title: Radiology doi: 10.1148/radiol.2021211374 contributor: fullname: Queler – volume: 1 start-page: 30 year: 1996 ident: ref_20 article-title: Forming inferences about some intraclass correlation coefficients publication-title: Psychol. Methods doi: 10.1037/1082-989X.1.1.30 contributor: fullname: McGraw – volume: 79 start-page: 312 year: 2010 ident: ref_60 article-title: Personality Features and Personality Disorders in Chronic Fatigue Syndrome: A Population-Based Study publication-title: Psychother. Psychosom. doi: 10.1159/000319312 contributor: fullname: Nater – ident: ref_23 – volume: 29 start-page: 51 year: 1965 ident: ref_24 article-title: The inheritance of liability to certain diseases, estimated from the incidence among relatives publication-title: Ann. Hum. Genet. doi: 10.1111/j.1469-1809.1965.tb00500.x contributor: fullname: Falconer – volume: 52 start-page: 13 year: 2021 ident: ref_10 article-title: Gene-by-Crisis Interaction for Optimism and Meaning in Life: The Effects of the COVID-19 Pandemic publication-title: Behav. Genet. contributor: fullname: Pelt – volume: 71 start-page: 515 year: 2021 ident: ref_42 article-title: Fatigue bei Long COVID publication-title: Psychother. Psychosom. Med. Psychol. doi: 10.1055/a-1544-8349 contributor: fullname: Stengel – ident: ref_40 doi: 10.1371/journal.pone.0240784 – ident: ref_4 – volume: 13 start-page: 404 year: 2021 ident: ref_49 article-title: A Novel Case of Bifacial Diplegia Variant of Guillain-Barré Syndrome Following Janssen COVID-19 Vaccination publication-title: Neurol. Int. doi: 10.3390/neurolint13030040 contributor: fullname: Prasad – volume: 39 start-page: 315 year: 1995 ident: ref_18 article-title: The multidimensional fatigue inventory (MFI) psychometric qualities of an instrument to assess fatigue publication-title: J. Psychosom. Res. doi: 10.1016/0022-3999(94)00125-O contributor: fullname: Smets – ident: ref_46 doi: 10.1515/znc-2022-0092 – volume: 35 start-page: 1327 year: 2005 ident: ref_27 article-title: Twin analyses of chronic fatigue in a Swedish national sample publication-title: Psychol. Med. doi: 10.1017/S0033291705005222 contributor: fullname: Sullivan – volume: 8 start-page: e129 year: 2022 ident: ref_13 article-title: The consequences of a year of the COVID-19 pandemic for the mental health of young adult twins in England and Wales publication-title: BJPsych Open doi: 10.1192/bjo.2022.506 contributor: fullname: Rimfeld – volume: 64 start-page: 1298 year: 2021 ident: ref_14 article-title: Medizinische Zwillingsforschung in Deutschland publication-title: Bundesgesundheitsblatt-Gesundh. -Gesundh. doi: 10.1007/s00103-021-03400-2 contributor: fullname: Enck – volume: 8 start-page: 1073 year: 2021 ident: ref_43 article-title: Persistent neurologic symptoms and cognitive dysfunction in non-hospitalized Covid-19 “long haulers” publication-title: Ann. Clin. Transl. Neurol. doi: 10.1002/acn3.51350 contributor: fullname: Graham – volume: 2 start-page: 100122 year: 2022 ident: ref_1 article-title: Mental health consequences of COVID-19 pandemic among college students and coping approaches adapted by higher education institutions: A scoping review publication-title: SSM-Ment. Health doi: 10.1016/j.ssmmh.2022.100122 contributor: fullname: Pandya – volume: 10 start-page: 679 year: 2019 ident: ref_15 article-title: Are Individual Learning Experiences More Important Than Heritable Tendencies? A Pilot Twin Study on Placebo Analgesia publication-title: Front. Psychiatry doi: 10.3389/fpsyt.2019.00679 contributor: fullname: Weimer – volume: 77 start-page: 711 year: 2021 ident: ref_55 article-title: The relationship between coronavirus 19 fear and occupational fatigue, burnout and recovery levels in healthcare professionals in Turkey publication-title: Arch. Environ. Occup. Health – volume: 99 start-page: 120 year: 2017 ident: ref_45 article-title: Biopsychosocial risk factors of persistent fatigue after acute infection: A systematic review to inform interventions publication-title: J. Psychosom. Res. doi: 10.1016/j.jpsychores.2017.06.013 contributor: fullname: Hulme – volume: 3 start-page: 872 year: 2002 ident: ref_6 article-title: Classical twin studies and beyond publication-title: Nat. Rev. Genet. doi: 10.1038/nrg932 contributor: fullname: Boomsma – volume: 52 start-page: 191 year: 2022 ident: ref_33 article-title: Postcovid-19 Asthenic Syndrome publication-title: Neurosci. Behav. Physiol. doi: 10.1007/s11055-022-01222-6 contributor: fullname: Zolotovskaia – ident: ref_3 – volume: 50 start-page: 102430 year: 2022 ident: ref_54 article-title: Evaluation of fatigue and sleep problems in cabin crews during the early COVID-19 pandemic period publication-title: Travel Med. Infect. Dis. doi: 10.1016/j.tmaid.2022.102430 contributor: fullname: Sabaner – volume: 6 start-page: 100122 year: 2021 ident: ref_41 article-title: Post-COVID syndrome in non-hospitalised patients with COVID-19: A longitudinal prospective cohort study publication-title: Lancet Reg. Health-Eur. contributor: fullname: Augustin – volume: 10 start-page: 160 year: 2022 ident: ref_30 article-title: The role of pain and psychological distress in fatigue: A co-twin and within-person analysis of confounding and causal relations publication-title: Health Psychol. Behav. Med. doi: 10.1080/21642850.2022.2033121 contributor: fullname: Andelic – volume: 13 start-page: 947973 year: 2022 ident: ref_37 article-title: Post-COVID-19 fatigue: A systematic review publication-title: Front. Psychiatry doi: 10.3389/fpsyt.2022.947973 contributor: fullname: Joli – volume: 14 start-page: e26344 year: 2022 ident: ref_34 article-title: The Dimensionality of the Multidimensional Fatigue Inventory (MFI-20) Derived From Healthy Adults and Patient Subpopulations: A Challenge for Clinicians publication-title: Cureus contributor: fullname: Bakalidou – ident: ref_47 – volume: 12 start-page: 9156 year: 2022 ident: ref_58 article-title: Personality and fatigue: Meta-analysis of seven prospective studies publication-title: Sci. Rep. doi: 10.1038/s41598-022-12707-2 contributor: fullname: Stephan – volume: 314 start-page: 114678 year: 2022 ident: ref_7 article-title: Genetic and environmental contributions to psychopathological symptoms stability and change across the COVID-19 pandemic publication-title: Psychiatry Res. doi: 10.1016/j.psychres.2022.114678 contributor: fullname: Gigantesco – volume: 26 start-page: 140 year: 2003 ident: ref_32 article-title: Fatigue in the General Population publication-title: Oncol. Res. Treat. doi: 10.1159/000069834 contributor: fullname: Schwarz – volume: 153 start-page: 106860 year: 2021 ident: ref_51 article-title: Symptomology following mRNA vaccination against SARS-CoV-2 publication-title: Prev. Med. doi: 10.1016/j.ypmed.2021.106860 contributor: fullname: Ebinger – volume: 51 start-page: 110 year: 2021 ident: ref_12 article-title: Genetic Correlates of Psychological Responses to the COVID-19 Crisis in Young Adult Twins in Great Britain publication-title: Behav. Genet. doi: 10.1007/s10519-021-10050-2 contributor: fullname: Rimfeld – ident: ref_17 doi: 10.1371/journal.pone.0123992 – volume: 13 start-page: e13524 year: 2021 ident: ref_52 article-title: Lymphadenopathy Associated With the COVID-19 Vaccine publication-title: Cureus contributor: fullname: Hiller – ident: ref_50 doi: 10.1177/21501319221089255 – volume: 44 start-page: 101323 year: 2021 ident: ref_35 article-title: The physical and mental health of the medical staff in Wuhan Huoshenshan Hospital during COVID-19 epidemic: A Structural Equation Modeling approach publication-title: Eur. J. Integr. Med. doi: 10.1016/j.eujim.2021.101323 contributor: fullname: Wang – volume: 37 start-page: 1078 year: 1999 ident: ref_36 article-title: Gender Differences in Fatigue publication-title: Med. Care doi: 10.1097/00005650-199910000-00011 contributor: fullname: Bensing – volume: 6 start-page: 284 year: 1994 ident: ref_21 article-title: Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology publication-title: Psychol. Assess. doi: 10.1037/1040-3590.6.4.284 contributor: fullname: Cicchetti – volume: 45 start-page: 289 year: 2013 ident: ref_59 article-title: Chronic Fatigue and Personality: A Twin Study of Causal Pathways and Shared Liabilities publication-title: Ann. Behav. Med. doi: 10.1007/s12160-012-9463-5 contributor: fullname: Poeschla – volume: 197 start-page: 106 year: 2010 ident: ref_29 article-title: Aetiology of fatigue in Sri Lanka and its overlap with depression publication-title: Br. J. Psychiatry doi: 10.1192/bjp.bp.109.069674 contributor: fullname: Ball – volume: 20 start-page: 410 year: 2020 ident: ref_57 article-title: Asymptomatic cases in a family cluster with SARS-CoV-2 infection publication-title: Lancet Infect. Dis. doi: 10.1016/S1473-3099(20)30114-6 contributor: fullname: Pan – ident: ref_48 doi: 10.3390/vaccines10040488 – volume: 46 start-page: 125 year: 2020 ident: ref_39 article-title: Chronic Illness and Fatigue in Older Individuals: A Systematic Review publication-title: Rehabil. Nurs. doi: 10.1097/RNJ.0000000000000278 contributor: fullname: Torossian – volume: 86 start-page: 420 year: 1979 ident: ref_19 article-title: Intraclass correlations: Uses in assessing rater reliability publication-title: Psychol. Bull. doi: 10.1037/0033-2909.86.2.420 contributor: fullname: Shrout – volume: 296 start-page: 113699 year: 2020 ident: ref_8 article-title: Fear and depression linked to COVID-19 exposure A study of adult twins during the COVID-19 pandemic publication-title: Psychiatry Res. doi: 10.1016/j.psychres.2020.113699 contributor: fullname: Tsang – volume: 252 start-page: 184 year: 2002 ident: ref_16 article-title: The Swedish Twin Registry: A unique resource for clinical, epidemiological and genetic studies publication-title: J. Intern. Med. doi: 10.1046/j.1365-2796.2002.01032.x contributor: fullname: Lichtenstein |
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Title | Is the Pandemic Wearing Us Out? A Cross-Sectional Study of the Prevalence of Fatigue in Adult Twins without Previous SARS-CoV-2 Infection |
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