Comparison of Direct and Extraction Immunoassay Methods With Liquid Chromatography-Tandem Mass Spectrometry Measurement of Urinary Free Cortisol for the Diagnosis of Cushing’s Syndrome

• Published in: Annals of laboratory medicine Vol. 44; no. 1; pp. 29 - 37
• Main Authors: Mu, Danni, Fang, Jiadan, Yu, Songlin, Ma, Yichen, Cheng, Jin, Hu, Yingying, Song, Ailing, Zhao, Fang, Zhang, Qi, Qi, Zhihong, Zhang, Kui, Xia, Liangyu, Qiu, Ling, Zhu, Huijuan, Cheng, Xinqi
• Format: Journal Article
• Language: English
• Published: Korean Society for Laboratory Medicine 01.01.2024; 대한진단검사의학회
• Subjects: Original; 병리학

Twenty-four-hour urinary free cortisol (UFC) measurement is the initial diagnostic test for Cushing's syndrome (CS). We compared UFC determination by both direct and extraction immunoassays using Abbott Architect, Siemens Atellica Solution, and Beckman DxI800 with liquid chromatography-tandem m...