Blood Test Increases Colorectal Cancer Screening in Persons Who Declined Colonoscopy and Fecal Immunochemical Test: A Randomized Controlled Trial

• Published in: Clinical gastroenterology and hepatology Vol. 21; no. 11; pp. 2951 - 2957.e2
• Main Authors: Liang, Peter S., Zaman, Anika, Kaminsky, Anne, Cui, Yongyan, Castillo, Gabriel, Tenner, Craig T., Sherman, Scott E., Dominitz, Jason A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2023
• Subjects: Colonoscopy - methods; Colorectal Neoplasms - diagnosis; Colorectal Neoplasms - prevention & control; Early Detection of Cancer - methods; Humans; Liquid Biopsy; Mass Screening - methods; Occult Blood; Second-Line; Septin 9; Veteran; FIT; USPSTF; Liquid Biopsy; FDA; Second-Line; VA; Veteran; Septin 9

The septin 9 blood test is indicated for colorectal cancer screening in individuals who decline first-line tests, but participation in this context is unclear. We conducted a randomized controlled trial to compare reoffering colonoscopy and fecal immunochemical test (FIT) alone versus also offering...