The effect of supplementing the calcium phosphate cement containing poloxamer 407 on cellular activities

• Published in: Journal of biomedical materials research. Part B, Applied biomaterials Vol. 112; no. 1; pp. e35335 - n/a
• Main Authors: Kim, Yeeun, Hamada, Kenichi, Sekine, Kazumitsu
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.01.2024; Wiley Subscription Services, Inc
• Subjects: Ball milling; Biological effects; Biomedical materials; Block copolymers; Bone grafts; Bone growth; Bone healing; calcium phosphate cement; Calcium phosphates; Cell adhesion; Cell viability; Cement; Crystal defects; Crystals; Cytoplasm; cytotoxicity; Fracture toughness; Hydroxyapatite; Materials research; Materials science; Mechanical properties; Poloxamer 407; Poloxamers; Regeneration; Regeneration (physiology); Risk reduction; Surfactants; Tricalcium phosphate; β–TCP; Poloxamer 407; cell adhesion; cytotoxicity; β-TCP; calcium phosphate cement

Calcium phosphate cement (CPC) is generally used for bone repair and augmentation. Poloxamers are tri‐block copolymers that are used as surfactants but have applications in drug and antibiotic delivery. However, their biological effects on bone regeneration systems remain unelucidated. Here, we aime...