Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects - Chung, J-Y; Cho, J-Y; Yu, K-S; Kim, J-R; Lim, K S; Sohn, D-R; Shin, S-G; Jang, I-J (Clinical pharmacology and therapeutics, 2008)
Keywords: Adult; Anticonvulsants - administration & dosage; Anticonvulsants - blood; Anticonvulsants - pharmacokinetics; Anticonvulsants - pharmacology; Area Under Curve; Female; Glucuronosyltransferase - genetics; Humans; Lorazepam - administration & dosage; Lorazepam - blood; Lorazepam - pharmacokinetics; Lorazepam - pharmacology; Male; Polymorphism, Genetic; Psychometrics; Psychomotor Performance - drug effects; Valproic Acid - administration & dosage; Valproic Acid - blood; Valproic Acid - pharmacokinetics; Valproic Acid - pharmacology