Contrast subgraphs catch patterns of altered functional connectivity in autism spectrum disorder

• Published in: Scientific reports Vol. 15; no. 1; pp. 24265 - 12
• Main Authors: Lanciano, Tommaso, Petri, Giovanni, Gili, Tommaso, Bonchi, Francesco
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 07.07.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 639/766/530/2801; 692/699/476/1373; Adolescent; Adult; Age groups; Autism; Autism spectrum disorder; Autism Spectrum Disorder - diagnostic imaging; Autism Spectrum Disorder - physiopathology; Biomarkers; Brain; Brain - physiopathology; Brain Mapping; Child; Connectome - methods; Contrast subgraphs; Cortex (parietal); Datasets; Developmental stages; Female; Frontal gyrus; Functional brain networks; Functional connectivity; Graphs; Humanities and Social Sciences; Humans; Magnetic Resonance Imaging; Male; multidisciplinary; Nerve Net - physiopathology; Network neuroscience; Neural networks; Occipital lobe; Parietal Lobe - physiopathology; Science; Science (multidisciplinary); Structure-function relationships; Teenagers; Temporal lobe; Young Adult; Functional connectivity; Contrast subgraphs; Network neuroscience; Functional brain networks; Autism spectrum disorder

Despite the breakthrough achievements in understanding structural and functional alterations of brain connectivity in autism spectrum disorder (ASD), the exact nature and type of such alterations are not yet clear due to conflicting reports of hyper-connectivity, hypo-connectivity, and—in some cases...