TRPM7 overexpression enhances the cancer stem cell-like and metastatic phenotypes of lung cancer through modulation of the Hsp90α/uPA/MMP2 signaling pathway - Liu, Kai; Xu, Shao-Hua; Chen, Zhao; Zeng, Qing-Xin; Li, Zhi-Jun; Chen, Zhou-Miao (BMC cancer, 2018)
Keywords: Apoptosis; Breast cancer; cancer stem cells; Cancer therapies; Cell cycle; Cell Line, Tumor; Chemotherapy; Fatalities; Gelatinase A; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins - metabolism; Humans; Immunohistochemistry; Kinases; KLF4 protein; Lung Cancer; Lung Neoplasms - genetics; Lung Neoplasms - metabolism; Lung Neoplasms - mortality; Lung Neoplasms - pathology; Lymph nodes; Matrix Metalloproteinase 2 - metabolism; Medical prognosis; Mesenchyme; Metastases; Metastasis; Motility; Neoplasm Metastasis; Neoplasm Staging; Neoplastic Stem Cells - metabolism; Phenotype; Phenotypes; Phytochemicals; Prognosis; Protein Kinase Inhibitors - pharmacology; Protein-Serine-Threonine Kinases - antagonists & inhibitors; Protein-Serine-Threonine Kinases - genetics; Signal Transduction; Stem cells; Transient receptor potential proteins; TRPM Cation Channels - antagonists & inhibitors; TRPM Cation Channels - genetics; TRPM7; Waixenicin A; TRPM7; Lung Cancer; cancer stem cells; Waixenicin A