A small key unlocks a heavy door: The essential function of the small hydrophobic proteins SP-B and SP-C to trigger adsorption of pulmonary surfactant lamellar bodies - Hobi, Nina; Giolai, Michael; Olmeda, Bárbara; Miklavc, Pika; Felder, Edward; Walther, Paul; Dietl, Paul; Frick, Manfred; Pérez-Gil, Jesus; Haller, Thomas (Biochimica et biophysica acta, 2016)
Keywords: Adsorption; Alveolar Epithelial Cells - drug effects; Alveolar Epithelial Cells - metabolism; Alveolar Epithelial Cells - secretion; Alveolar Epithelial Cells - ultrastructure; Animals; ARDS; Boron Compounds; Cells, Cultured; Compliance; Exocytosis; Fluorescent Dyes; Heterocyclic Compounds, 3-Ring; Hydrophobic and Hydrophilic Interactions; Lamellar body; Lung injury; Microscopy, Confocal; Organelles - drug effects; Organelles - metabolism; Pulmonary Surfactant-Associated Protein B - antagonists & inhibitors; Pulmonary Surfactant-Associated Protein B - pharmacology; Pulmonary Surfactant-Associated Protein B - physiology; Pulmonary Surfactant-Associated Protein C - antagonists & inhibitors; Pulmonary Surfactant-Associated Protein C - pharmacology; Pulmonary Surfactant-Associated Protein C - physiology; Pulmonary Surfactants - chemistry; Rats; Rats, Sprague-Dawley; Surface Properties; Surface Tension; Surface tension; Compliance; ARDS; Lamellar body; Lung injury