Association between serum cell adhesion molecules with hs-CRP, uric acid and VEGF genetic polymorphisms in subjects with metabolic syndrome

• Published in: Molecular biology reports Vol. 47; no. 2; pp. 867 - 875
• Main Authors: Ghazizadeh, Hamideh, Rezaei, Majid, Avan, Amir, Fazilati, Mohammad, Pasdar, Alireza, Tavallaie, Shima, Kazemi, Elham, Seyedi, Seyed Mohammad Reza, Ferns, Gordon A., Azimi-Nezhad, Mohsen, Ghayour-Mobarhan, Majid
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.02.2020; Springer Nature B.V
• Subjects: adhesion; Adult; Animal Anatomy; Animal Biochemistry; Arteriosclerosis; atherosclerosis; biomarkers; Biomarkers - blood; Biomedical and Life Sciences; blood serum; C-reactive protein; C-Reactive Protein - analysis; Cardiovascular diseases; cell adhesion; Cell adhesion & migration; Cell adhesion molecules; Cell Adhesion Molecules - analysis; Cell Adhesion Molecules - blood; Cell Adhesion Molecules - genetics; Cholesterol - analysis; Cholesterol - blood; Cross-Sectional Studies; diabetes; Diabetes mellitus; Diabetes Mellitus - blood; E-selectin; E-Selectin - blood; E-Selectin - genetics; Enzyme-linked immunosorbent assay; Female; genes; Genetic diversity; Health risk assessment; heart; High density lipoprotein; Histology; Humans; Inflammation; Intercellular adhesion molecule 1; Intercellular Adhesion Molecule-1 - blood; Intercellular Adhesion Molecule-1 - genetics; Life Sciences; Male; Metabolic syndrome; Metabolic Syndrome - blood; Metabolic Syndrome - genetics; Metabolic Syndrome - metabolism; Middle Aged; molecular biology; Morphology; Original Article; regression analysis; Risk Factors; stroke; Triglycerides - blood; Uric acid; Uric Acid - analysis; Uric Acid - blood; Vascular endothelial growth factor; Vascular Endothelial Growth Factor A - genetics; Vascular Endothelial Growth Factor A - metabolism; vascular endothelial growth factors; Metabolic syndrome; Vascular endothelial growth factor; Cell adhesion molecules; Polymorphism

Metabolic syndrome (MetS) is associated with a pro-inflammatory state and endothelial dysfunction that places subjects with MetS at a higher risk of atherosclerosis. Inflammatory biomarkers are raised in patients at risk of developing cardiovascular diseases. In the current study, we aimed to examin...