Formalin fixed paraffin embedded (FFPE) material is amenable to HPV detection by the Xpert® HPV assay

• Published in: Journal of clinical virology Vol. 77; pp. 55 - 59
• Main Authors: Guerendiain, Daniel, Moore, Catherine, Wells, Lucy, Conn, Brendan, Cuschieri, Kate
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2016
• Subjects: Allergy and Immunology; Biopsy; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - etiology; DNA, Viral; FFPE; Histological Techniques; HPV; Humans; Infectious Disease; Oropharyngeal; Oropharyngeal Neoplasms - diagnosis; Oropharyngeal Neoplasms - etiology; p16; Papillomaviridae - genetics; Papillomavirus Infections - complications; Papillomavirus Infections - diagnosis; Papillomavirus Infections - virology; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; Squamous cell carcinoma; Oropharyngeal; Squamous cell carcinoma; p16; FFPE; Biopsy; HPV

Highlights • There is an increasing demand for HPV annotation of FFPE material. • The performance of the Xpert® HPV assay, was assessed for FFPE material. • FFPE material is amenable to HPV detection by the Xpert assay.