Independent associations of lymphopenia and neutropenia in patients with systemic lupus erythematosus: a longitudinal, multinational study

• Published in: Rheumatology (Oxford, England) Vol. 60; no. 11; pp. 5185 - 5193
• Main Authors: Kandane-Rathnayake, Rangi, Louthrenoo, Worawit, Golder, Vera, Luo, Shue-Fen, Wu, Yeong-Jian J, Lateef, Aisha, Cho, Jiacai, Li, Zhanguo, An, Yuan, Hamijoyo, Laniyati, Navarra, Sandra, Zamora, Leonid, Katsumata, Yasuhiro, Harigai, Masayoshi, Sockalingam, Sargunan, Chan, Madelynn, Chen, Yi-Hsing, O'Neill, Sean, Goldblatt, Fiona, Hao, Yanjie, Zhang, Zhuoli, Kikuchi, Jun, Takeuchi, Tsutomu, Lau, Chak Sing, Nikpour, Mandana, Morand, Eric, Hoi, Alberta
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 03.11.2021
• Subjects: Adult; Clinical Science; Female; Humans; Immunosuppressive Agents - adverse effects; Longitudinal Studies; Lupus Erythematosus, Systemic - drug therapy; Lupus Erythematosus, Systemic - immunology; Lymphopenia - chemically induced; Male; Middle Aged; Neutropenia - chemically induced; SLE disease activity; leucopenia; neutropenia; LLDAS; lymphopenia; medications

The prevalence and associations of leucopenia in SLE remain incompletely understood. We evaluated associations of disease activity and medication use with leucopenia (lymphopenia and neutropenia) in a multinational, prospectively followed SLE cohort. Data from the Asia Pacific Lupus Collaboration co...