Continuous Antibiotic Prophylaxis in Pediatric Urology

Continuous antibiotic prophylaxis (CAP) for urinary tract infection prevention in children with vesicoureteral reflux, hydronephrosis, and hydroureteronephrosis is reviewed. A more selective use of CAP is advocated based on a review of known individual risk factors in each of these conditions that s...

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Published inUrologic clinics of North America Vol. 45; no. 4; pp. 525 - 538
Main Authors Storm, Douglas W., MD, Braga, Luis H., MD, PhD, Cooper, Christopher S., MD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.11.2018
Subjects
Antibiotic prophylaxis
Antibiotic resistance
Megaureter
Microbiota
Prenatal hydronephrosis
Side effects
Urology
Vesicoureteral reflux
Antibiotic prophylaxis
Microbiota
Megaureter
Side effects
Vesicoureteral reflux
Antibiotic resistance
Prenatal hydronephrosis
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Abstract Continuous antibiotic prophylaxis (CAP) for urinary tract infection prevention in children with vesicoureteral reflux, hydronephrosis, and hydroureteronephrosis is reviewed. A more selective use of CAP is advocated based on a review of known individual risk factors in each of these conditions that subsequently helps identify the children most likely to benefit from CAP. Both short-term and potential long-term side effects of CAP are reviewed, including the impact of prophylactic antibiotics on bacterial resistance and the microbiome. Alternatives to continuous antibiotic prophylaxis including Vaccinium macrocarpon (Cranberry), probiotics, and vaccines are reviewed.
AbstractList Continuous antibiotic prophylaxis (CAP) for urinary tract infection prevention in children with vesicoureteral reflux, hydronephrosis, and hydroureteronephrosis is reviewed. A more selective use of CAP is advocated based on a review of known individual risk factors in each of these conditions that subsequently helps identify the children most likely to benefit from CAP. Both short-term and potential long-term side effects of CAP are reviewed, including the impact of prophylactic antibiotics on bacterial resistance and the microbiome. Alternatives to continuous antibiotic prophylaxis including Vaccinium macrocarpon (Cranberry), probiotics, and vaccines are reviewed.
Author Storm, Douglas W., MD
Cooper, Christopher S., MD
Braga, Luis H., MD, PhD
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Issue 4
Keywords Antibiotic prophylaxis
Microbiota
Megaureter
Side effects
Vesicoureteral reflux
Antibiotic resistance
Prenatal hydronephrosis
Language English
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SubjectTerms Antibiotic prophylaxis
Antibiotic resistance
Megaureter
Microbiota
Prenatal hydronephrosis
Side effects
Urology
Vesicoureteral reflux
Title Continuous Antibiotic Prophylaxis in Pediatric Urology
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https://dx.doi.org/10.1016/j.ucl.2018.06.001
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