Jaboticaba (Myrciaria cauliflora) Fruit Extract Suppressed Aberrant Crypt Formation in 1,2-Dimetylhydrazine-Induced Rats

• Published in: Plant foods for human nutrition (Dordrecht) Vol. 78; no. 2; pp. 286 - 291
• Main Authors: Ardanareswari, Katharina, Lowisia, Webiana, Soedarini, Bernadeta, Liao, Jiunn-Wang, Chung, Yun-Chin
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.06.2023; Springer Nature B.V
• Subjects: 1,2-Dimethylhydrazine; Biomarkers; butyrates; Cancer; carcinogenesis; Cecum; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Colorectal cancer; Colorectal carcinoma; colorectal neoplasms; Composition; Crypts; Dimethylhydrazines; Dosage; Ecology; Ellagic acid; Fatty acids; Food Science; fruit extracts; Fruits; Gallic acid; Institutional Animal Care and Use Committee; Intestinal microflora; intestinal microorganisms; Metagenomics; Microbiota; Microorganisms; Myrciaria cauliflora; Nutrition; Phenolic compounds; Phenols; Plant Physiology; Plinia cauliflora; probability; rRNA 16S; short chain fatty acids; Survival; survival rate; Tumorigenesis; Gut microbiota; 16s rDNA; Sprague-Dawley rats; SCFA; Whole fruit; Colorectal cancer

Early intervention can significantly improve the colorectal cancer survival rate. Foods rich in phenolic compounds, such as jaboticaba ( Myrciaria cauliflora ), may prevent tumorigenesis. We investigated the effectivity of jaboticaba whole fruit ethanolic extract (FEX) in suppressing aberrant crypt...