Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: Comparison to chronic phencyclidine and MK-801

• Published in: Pharmacology, biochemistry and behavior Vol. 175; pp. 89 - 100
• Main Authors: Hámor, Peter U., Šírová, Jana, Páleníček, Tomáš, Zaniewska, Magdalena, Bubeníková-Valešová, Věra, Schwendt, Marek
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2018
• Subjects: 5-HT2A; Heterocomplex; Methamphetamine; mGlu2; MK-801; Phencyclidine; Heterocomplex; MK-801; Phencyclidine; mGlu2; Methamphetamine; 5-HT2A

Chronic methamphetamine (meth) abuse often turns into a compulsive drug-taking disorder accompanied by persistent cognitive deficits and re-occurring psychosis. Possible common neurobiological substrates underlying meth-induced deficits and schizophrenia remain poorly understood. Serotonin 2A (5-HT2...