Quercetin attenuates cisplatin-induced fat loss

• Published in: European journal of nutrition Vol. 60; no. 4; pp. 1781 - 1793
• Main Authors: Lin, Yi-Chin, Chen, Li-wen, Chen, Yun-Chu, Chan, Shu-Ting, Liao, Jiunn-Wang, Yeh, Shu-Lan
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2021; Springer Nature B.V
• Subjects: antineoplastic activity; Body weight; Body weight loss; Cancer; Chemistry; Chemistry and Materials Science; Chemotherapy; Cisplatin; epididymis; Fat metabolism; Flavonoids; Food intake; Gene expression; Intelligence; intraperitoneal injection; lipid metabolism; liver; Metabolism; muscles; Nutrition; Original Contribution; p53 Protein; protective effect; Quercetin; Fat metabolism; Fat loss; Cisplatin; Quercetin

Purpose The major aim of the present study was to determine the effects of quercetin, a well-known flavonoid, on attenuating cisplatin (CDDP)-induced fat loss and the possible mechanisms. Methods Tumor-bearing nude mice and tumor-free BALB/c mice were administrated with CDDP alone or in combination...