Signal transducer and activator of transcription 3 (STAT3) homologue in turbot ( Scophthalmus maximus): Molecular characterization and expression analysis

• Published in: Fish & shellfish immunology Vol. 30; no. 1; pp. 255 - 262
• Main Authors: Wang, Na, Yang, Chang-Geng, Sun, Zhong-Zhi, Wang, Xian-Li, Chen, Song-Lin
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 2011
• Subjects: Amino Acid Sequence; amino acids; Animals; bacterial infections; Base Sequence; Cloning, Molecular; complementary DNA; conserved sequences; cytokines; disease resistance; DNA Virus Infections - metabolism; DNA Virus Infections - veterinary; DNA Virus Infections - virology; DNA, Complementary - genetics; DNA, Complementary - metabolism; fish diseases; Fish Diseases - immunology; Fish Diseases - metabolism; Flatfishes - metabolism; Freshwater; gene expression regulation; Gene Expression Regulation - immunology; Gene Expression Regulation - physiology; genes; Hepcidin; Immune defense; immunity; Iridoviridae; kidneys; liver; Lymphocystivirus; Marine; messenger RNA; molecular cloning; Molecular Sequence Data; nucleotides; pathogens; Phylogeny; polypeptides; reverse transcriptase polymerase chain reaction; Scophthalmus maximus; signal transduction; Siniperca; Siniperca chuatsi; spleen; STAT3; STAT3 Transcription Factor - chemistry; STAT3 Transcription Factor - genetics; STAT3 Transcription Factor - metabolism; tissue distribution; transcription factors; turbot; Turbot ( Scophthalmus maximus); Vibrio anguillarum; Vibrio Infections - immunology; Vibrio Infections - metabolism; Vibrio Infections - veterinary; Vibrio anguillarum; Immune defense; Turbot ( Scophthalmus maximus); Hepcidin; STAT3

Signal transducer and activator of transcription 3 (STAT3) acts as an important mediator in multiple biological processes induced by different cytokines. So far, little information is available in fish STAT3. In this study, turbot ( Scophthalmus maximus) STAT3 gene was cloned and characterized for t...