Role and predictive value of microRNAs 204 and 210 in the diagnosis of pulmonary arterial hypertension and the distinction between idiopathic, systemic sclerosis, and schistosomiasis-associated pulmonary arterial hypertension

• Published in: Egyptian Journal of Bronchology Vol. 18; no. 1; pp. 37 - 10
• Main Authors: Dimitry, Mark O., Amin, Yosef M., ElKorashy, Reem I., Raslan, Hala M., Kamel, Solaf A., Hassan, Eman M., Yousef, Rasha N., Awadallah, Eman A.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2024; Springer; Springer Nature B.V; SpringerOpen
• Subjects: Biomarkers; Cardiac catheterization; Catheterization; Catheters; Critical Care Medicine; Disease; Dyspnea; Genes; Idiopathic PAH; Intensive; Intubation; Lungs; Medical prognosis; Medicine; Medicine & Public Health; MicroRNA; MicroRNAs; miR-204; miR-210; Mortality; Pathogenesis; Pneumology/Respiratory System; Pulmonary arterial hypertension; Pulmonary arteries; Pulmonary hypertension; Sch-PAH; Schistosomiasis; Scleroderma; Scleroderma (Disease); SSc-PAH; Systemic scleroderma; Veins & arteries; United States > US; Germany; miR-204; Echocardiography; Idiopathic PAH; miR-210; Sch-PAH; Pulmonary arterial hypertension; Right heart catheterization; SSc-PAH

Background Pulmonary arterial hypertension is most of the time diagnosed late in the course of the disease and necessitates right cardiac catheterization which is an invasive and costly tool. MicroRNAs have a role in the pathogenesis of pulmonary hypertension, systemic sclerosis, and schistosomiasis...