Exposure to organophosphate ester flame retardants and plasticizers and associations with preeclampsia and blood pressure in pregnancy

• Published in: Environmental research Vol. 262; no. Pt 2; p. 119910
• Main Authors: Lueth, Amir J., Bommarito, Paige A., Stevens, Danielle R., Welch, Barrett M., Cantonwine, David E., Ospina, Maria, Calafat, Antonia M., Meeker, John D., McElrath, Thomas F., Ferguson, Kelly K.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.12.2024
• Subjects: Adult; Blood pressure; Blood Pressure - drug effects; Chemical exposure; Esters - urine; Female; Flame retardants; Flame Retardants - analysis; Flame Retardants - toxicity; Humans; Hypertensive disorders of pregnancy; Maternal Exposure - adverse effects; Organophosphate; Organophosphates - urine; Plasticizers - toxicity; Pre-Eclampsia - chemically induced; Pre-Eclampsia - urine; Preeclampsia; Pregnancy; Young Adult; Flame retardants; Chemical exposure; Blood pressure; Organophosphate; Preeclampsia; Hypertensive disorders of pregnancy

Organophosphate esters (OPEs), flame retardants and plasticizers found widely in consumer products, may impact vascularization processes in pregnancy. Yet, the association between maternal exposure to OPEs and both preeclampsia and blood pressure during pregnancy remains understudied. Within the LIF...