Phosphorylation of the carboxyl-terminal region of dystrophin

• Published in: Biochemistry and cell biology Vol. 74; no. 4; p. 431
• Main Authors: Michalak, M, Fu, S Y, Milner, R E, Busaan, J L, Hance, J E
• Format: Journal Article
• Language: English
• Published: Canada 01.01.1996
• Subjects: Animals; Calcineurin; Calcium - metabolism; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases - metabolism; Calmodulin - metabolism; Calmodulin-Binding Proteins - metabolism; Casein Kinase II; CDC2 Protein Kinase - metabolism; Dystrophin - chemistry; Dystrophin - metabolism; Glycogen Synthase Kinase 3; Humans; Phosphoprotein Phosphatases - metabolism; Phosphorylation; Protein-Serine-Threonine Kinases - metabolism

Dystrophin is a protein product of the gene responsible for Duchenne and Becker muscular dystrophy. The protein is localized to the inner surface of sarcolemma and is associated with a group of membrane (glyco)proteins. Dystrophin links cytoskeletal actins via the dystrophin-associated protein compl...