mTOR in podocyte function Is rapamycin good for diabetic nephropathy?
Comment on: Inoki K, et al. J Clin Invest 2011; 121:2181-2196 and Gödel M, et al. J Clin Invest 2011; 121:2197-2209
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| Published in | Cell cycle (Georgetown, Tex.) Vol. 10; no. 20; pp. 3415 - 3416 |
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| Format | Journal Article |
| Language | English |
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United States
Taylor & Francis
15.10.2011
Landes Bioscience |
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| Abstract | Comment on: Inoki K, et al. J Clin Invest 2011; 121:2181-2196 and Gödel M, et al. J Clin Invest 2011; 121:2197-2209 |
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| AbstractList | Comment on: Inoki K, et al. J Clin Invest 2011; 121:2181-2196 and Gödel M, et al. J Clin Invest 2011; 121:2197-2209 |
| Author | Guan, Kun-Liang Lu, Min-Kan Gong, Xing-Guo |
| AuthorAffiliation | Department of Pharmacology and Moores Cancer Center; University of California San Diego; La Jolla, CA USA Institute of Biochemistry; College of Life Sciences; Zhejiang University; P. R. China |
| AuthorAffiliation_xml | – name: Institute of Biochemistry; College of Life Sciences; Zhejiang University; P. R. China – name: Department of Pharmacology and Moores Cancer Center; University of California San Diego; La Jolla, CA USA – name: 1 Institute of Biochemistry; College of Life Sciences; Zhejiang University; Hangzhou, China – name: 2 Department of Pharmacology and Moores Cancer Center; University of California, San Diego; La Jolla, CA USA |
| Author_xml | – sequence: 1 givenname: Min-Kan surname: Lu fullname: Lu, Min-Kan – sequence: 2 givenname: Xing-Guo surname: Gong fullname: Gong, Xing-Guo email: gongxg@zju.edu.cn, kuguan@ucsd.edu – sequence: 3 givenname: Kun-Liang surname: Guan fullname: Guan, Kun-Liang email: gongxg@zju.edu.cn, kuguan@ucsd.edu |
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| Cites_doi | 10.1038/ki.2010.513 10.1172/JCI44771 10.1172/JCI44774 10.1038/nrm3025 10.1152/physrev.00020.2002 |
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| Snippet | Comment on: Inoki K, et al. J Clin Invest 2011; 121:2181-2196 and Gödel M, et al. J Clin Invest 2011; 121:2197-2209 Comment on: Inoki K, et al. J Clin Invest 2011; 121:2181–2196 and Gödel M, et al. J Clin Invest 2011; 121:2197–2209 |
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| SubjectTerms | Animals Binding Biology Bioscience Calcium Cancer Cell Cycle Diabetic Nephropathies - drug therapy Diabetic Nephropathies - metabolism Landes Mechanistic Target of Rapamycin Complex 1 Mice Mice, Knockout Monomeric GTP-Binding Proteins - metabolism Multiprotein Complexes Neuropeptides - metabolism Organogenesis Podocytes - metabolism Podocytes - physiology Proteins Proteins - antagonists & inhibitors Proteins - metabolism Ras Homolog Enriched in Brain Protein Signal Transduction - physiology Sirolimus - pharmacology Sirolimus - therapeutic use TOR Serine-Threonine Kinases - metabolism Tuberous Sclerosis Complex 1 Protein Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism |
| Subtitle | Is rapamycin good for diabetic nephropathy? |
| Title | mTOR in podocyte function |
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