Efficient synthesis of (±)-7-isopropyl-2,10-dimethyl-8(E),10-undecadien-4-one and 3,7-dimethyl-11-oxo-2(E),6(E)-dodecadienol (oxocrinol) under ultrasound
A simple and convergent synthesis of the title compounds has been achieved involving Zn–Cu couple catalysed conjugate addition of allylic halides to α,β-unsaturated carbonyl compounds promoted by ultrasonic waves in aqueous medium as a key step in good overall yields.
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Published in | Ultrasonics sonochemistry Vol. 8; no. 2; pp. 123 - 126 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
01.04.2001
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Subjects | |
Online Access | Get full text |
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